BAFF (TNFSF13B) Mouse Monoclonal Antibody [Clone ID: 2B]
Specifications
| Product Data | |
| Clone Name | 2B |
|---|---|
| Application | ELISA |
| Recommended Dilution | ELISA: 5 - 6µg/ml. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Recombinant full-length mature human CD257 expressed in E. coli. |
| Specificity | This antibody specifically recognises CD257 (otherwise known as BAFF/BLyS). This antibody has not been cross-adsorbed and may react with homologous proteins from related species. |
| Buffer | Phosphate buffered saline pH7.2 State: Purified State: Lyophilised purified IgG |
| Reconstitution Method | Reconstitute with 0.5ml distilled water |
| Concentration | lot specific |
| Purification | Affinity chromatography on Protein A |
| Conjugation | Unconjugated |
| Storage | Prior to reconstitution store at 2-8°C. Following reconstitution store the antibody at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Ambient |
| Gene Name | tumor necrosis factor superfamily member 13b |
| Database Link | |
| Background | CD257 is a 285 amino acid type II transmembrane protein and member of the tumor necrosis factor (TNF) superfamily of ligands, which acts as a B and T cell stimulator and plays a role in the development of autoimmune diseases such as systemic lupus erythematosus. CD257 is expressed by monocytes, macrophages, T cells and dendritic cells and acts through binding to CD267 (TACI), CD269 (BCMA) and CD268 (BAFFR) receptors, the latter interaction playing a critical role in the activation, survival, differentiation and proliferation of B cells. |
| Synonyms | TNFSF13B, BLYS, TALL1, TNFSF20, ZTNF4 |
| Reference Data | |
| Protein Categories | CD Markers, Cytokines, Intracellular Proteins, Membrane Proteins, Secreated Proteins |
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