SLC44A1 Mouse Monoclonal Antibody [Clone ID: VIM-15b]

CAT#: AM05591PU-T

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SLC44A1 mouse monoclonal antibody, clone VIM-15b, Purified



USD 204.00


Availability*
5 Days

Size
    • 25 ug


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Specifications

Product Data
Clone Name VIM-15b
Applications FC, IHC, IP
Recommended Dilution Flow Cytometry: Use 10 µl of 1/50-1/200 diluted antibody to label 1x106 cells in 100 µl. 
Immunoprecipitation.
Immunohistochemistry on Frozen Sections. 
Positive Control Tissue: 
Human tonsil.
Reactivity Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen MV4-11 acute monocyte leukaemia cells. 
Spleen cells from immunised Balb/c mice were fused with cells of the X63-Ag8.653 myeloma cell line.
Specificity This antibody is specific for the C-terminal variant of Human CDw92 (isoform 3), also known as CTL1.
Clone VIM-15b is reported to augment the LPS-induced production of IL-10 by monocyte-derived dendritic cells (Mo-DCs), and the reduced expression of CDw92 by Mo-DCs treated with ionomycin or calcium ionophore, can be reinduced in the presence of IL-10.
Formulation PBS, pH 7.4
State: Purified
State: Liquid purified IgG fraction from Tissue Culture Supernatant
Preservative: 0.09% Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein G
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background CDw92 is a 70kDa multi-pass membrane protein, expressed by monocytes, neutrophils, certain myeloid and T cell lines, and weakly by endothelial cells, fibroblasts and epithelial cells.
CDw92 is a member of the choline transporter-like protein family, so called due to their involvement in the efficient supply/transport of the natural amine choline, a vital cell nutrient required for the synthesis of cell membrane phospholipid components and the neurotransmitter acetylcholine.
Synonyms CDw92, CTL1
Reference Data
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