CD321 / JAM1 Rat Monoclonal Antibody [Clone ID: BV12]
Specifications
| Product Data | |
| Clone Name | BV12 |
|---|---|
| Application | ELISA, FC, IF |
| Recommended Dilution | Flow cytometry: The typical starting working dilution is 1:50. Immunoassays. Immunoflourescence. |
| Reactivity | Mouse |
| Antibody Host | Rat |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Specificity | This antibody recognizes junctional adhesion molecule-A (JAM-A), also known as JAM-1 and the mouse platelet F11-Receptor (F11R). |
| Buffer | PBS State: Purified State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% bovine serum albumin Preservative: 0.02% sodium azide |
| Concentration | lot specific |
| Purification | Protein G |
| Conjugation | Unconjugated |
| Storage | Store at 2 - 8 °C. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | F11 receptor |
| Database Link | |
| Background | JAM-A is a member of the immunoglobulin superfamily found on the surface of mouse platelets and at intercellular junctions of endothelial cells and epithelial cells. JAM-A belongs together with JAM-B (VE-JAM or JAM-3) and JAM-C (JAM-2) to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. In human JAM-A plays a role in platelet aggregation, secretion, adhesion and spreading. |
| Synonyms | JAM-A, Platelet F11 receptor, F11R, JCAM, PAM1 |
| Reference Data | |
| Protein Categories | CD Markers, Cytokines, Membrane Proteins |
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