Cytochrome P450 1A2 (CYP1A2) Mouse Monoclonal Antibody [Clone ID: 3B8C1]

CAT#: AM05371PU-N

Cytochrome P450 1A2 (CYP1A2) mouse monoclonal antibody, clone 3B8C1, Purified


USD 580.00

5 Days*

Size
    • 200 ug

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Specifications

Product Data
Clone Name 3B8C1
Applications IHC, WB
Recommended Dilution Western Blot: 1 - 2 µg/ml.
Immunohistochemistry: 1 - 5 µg/ml.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with rat cytochrome p450 proteins and mouse myeloma Ag8563 cells.
Specificity This antibody reacts to Cytochrome P450 1A2.
Formulation Phosphate buffered saline with 0.08% sodium azide
State: Purified
State: Liquid purified Ig
Concentration lot specific
Conjugation Unconjugated
Storage The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name cytochrome P450 family 1 subfamily A member 2
Background P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds. Several P450 enzymes have been classified by sequence similarities as members of the CYP1A and CYP2A subfamilies. NADPH cytochrome 450 reductase is a microsomal enzyme responsible for the transfer of electrons from NADPH to cytochrome P450 enzymes during the P450 catalytic cycle. NADPH cytochrome P450 reductase is localized to the endoplasmic reticulum where it is also able to transfer electrons to heme oxygenase and cytochrome β5. NADPH cytochrome P450 reductase is structurally related to two separate flavoprotein families, ferredoxin nucleotide reductase (FNR) and flavodoxin. Electron transfer of NADPH cytochrome P450 reductase requires the binding of two flavin cofactors, FAD and FMN, to the FNR and flavodoxin domains, respectively.
Synonyms Cytochrome P450 1A2, CYPIA2, Cytochrome P450-P3, Cytochrome P(3)450, Cytochrome P450 4
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.