Adra2b Mouse Monoclonal Antibody [Clone ID: 5G10]
$1,055.00
5 Days*
Specifications
| Product Data | |
| Clone Name | 5G10 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | Western blot (1-5 µg/ml). Immunohistochemistry. Positive Control/Tissue Expression: MDCK cells transfected with Rat alpha2B adrenergic receptors. |
| Reactivity | Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Synthetic peptide internal sequence corresponding to the third intracellular loop of Rat alpha 2b Adrenergic Receptor. |
| Buffer | PBS containing 0.08% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction. |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: One year from despatch. |
| Shipping | Blue Ice |
| Gene Name | adrenoceptor alpha 2B |
| Database Link | |
| Background | The rat alpha 2b adrenergic receptor is a G protein coupled receptor which acts through Gi2 and is responsible for Cellular communication and signal transduction. These receptors are linked to pertussis toxin-sensitive G proteins. Agonist binding leads to inhibition of adenylyl cyclase, inhibition of Ca(2+) channels and activation of K(+) channels. Recently, three distinct subtypes of alpha(2)-AR were described, alpha(2A)-AR, alpha(2B)-AR and alpha(2C)-AR. At present, it is unknown which of these alpha(2)-AR subtype(s) may regulate insulin secretion. |
| Synonyms | ADRA2L1, ADRA2RL1, Alpha-2B adrenoreceptor, Alpha-2B adrenoceptor |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.