Rb (RB1) Mouse Monoclonal Antibody [Clone ID: XZ91]
$775.00
5 Days*
Specifications
| Product Data | |
| Clone Name | XZ91 |
|---|---|
| Application | IP, WB |
| Recommended Dilution | Western Blot. Immunoprecipitation. |
| Reactivity | Chicken, Human, Mink, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Recombinant protein corresponding to amino acids 393-572 of the Human Retinoblastoma sequence. |
| Specificity | Recognizes Retinoblastoma (Rb). |
| Buffer | PBS containing 0.08% Sodium Azide as preservative. State: Purified State: Liquid (0.2µm sterile filtered) purified IgG fraction. |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store the antibody (in aliquots) at -20°C. Can be shipped at 2-8°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: One year from despatch. |
| Shipping | Blue Ice |
| Gene Name | RB transcriptional corepressor 1 |
| Database Link | |
| Background | Retinoblastoma encodes a phosphorylated protein p110 and binds and regulates E2F transcription factors. Rb functions as a major cell cycle regulator by its ability to repress gene transcription by all three RNA polymerases. In its hypophosphorylated form, Rb binds to a subset of E2F containing complexes converting them to repressors preventing expression of E2F target genes. These complexes repress transcription via E2F binding elements in the promotersof cell cycle control genes, such as E2F-1, c-myc, and cdc2 genes. |
| Synonyms | Retinoblastoma 1, Rb, p105-Rb, pRb, pp110, OSRC |
| Note | Predicted Molecular Weight: 105 kDa |
| Reference Data | |
| Atlas Protein Categories | ADC Targets, Cancer: Bladder, Cancer: Brain and CNS, Cancer: Gastrointestinal, Cancer: Haematopoietic and Lymphoid, Cancer: Lung, Cancer: Sarcoma, Growth Factors, Intracellular Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.