Cardiac Troponin I (TNNI3) (1-23) Mouse Monoclonal Antibody [Clone ID: B163M]

CAT#: AM05139PU-N

Cardiac Troponin I (TNNI3) (1-23) mouse monoclonal antibody, clone B163M, Purified

Specifications

Product Data

• Clone Name: B163M
• Applications: ELISA, IHC, IP, WB
• Recommended Dilution: Immunoassay.
  Immunoprecipitation.
  Immunohistochemistry.
  Immunoaffinity purification.
  Western blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human cTnI peptide
• Specificity: This antibody reacts with free cardiac troponin I (cTnI) and cTnI forming complexes with other troponin components. Not affected by heparin and phosphorylation. Recognizes an epitope located between amino acid residues 1 and 23 of cTnI. No cross-reactivity with skeletal muscle troponin I.
• Formulation: PBS, pH 7.4 containing 0,09% sodium azide
  State: Purified
  State: Liquid purified Ig
• Purification: Protein A chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.
  DO NOT FREEZE!
• Stability: Shelf life: one year from despatch.
• Gene Name: troponin I3, cardiac type
• Database Link:
  Entrez Gene 7137 Human
  UniProt ID P19429
• Background: Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.
• Synonyms: TNNI3, TNNC1