TSH beta (TSHB) Mouse Monoclonal Antibody [Clone ID: 204-12410]

SKU
AM05117PU-N
TSH beta (TSHB) mouse monoclonal antibody, clone 204-12410, Purified
  $720.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Clone Name 204-12410
Application ELISA
Recommended Dilution ELISA.
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human pituitary gland.
Specificity This antibody reacts to Thyroid Stimulating Hormone (TSH), beta subunit.
Cross-reactivity:
FSH: 0.7%
LH: 0.5%
TSH alpha: 1.5%
Buffer 10mM Phosphate, pH 7.4 containing 150mM Sodium chloride and 0,09% Sodium Azide as preservative.
State: Purified
State: Liquid (sterile filtered) purified fraction (>90% pure by SDS-PAGE).
Concentration lot specific
Purification Protein A Chromatography.
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C for one week or (in aliquots) at -40°C for longer.
If aliquoted for long term storage, fill volume should be equal to or greater than 50% of the nominal fill volume of the vial used.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name thyroid stimulating hormone beta
Database Link
Background Thyroid stimulating hormone, also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.
Synonyms Thyrotropin subunit beta, Thyroid-stimulating hormone subunit beta, TSH, TSHB, TSH beta
Reference Data
Atlas Protein Categories ADC Targets, Endocrine and metabolic diseases, Secreated Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.