PAI1 (SERPINE1) Mouse Monoclonal Antibody [Clone ID: 3E529]

SKU
AM05029PU-N
PAI1 (SERPINE1) mouse monoclonal antibody, clone 3E529, Purified
  $860.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Clone Name 3E529
Application ELISA
Recommended Dilution ELISA.
Reactivity Human
Antibody Host Mouse
Isotype IgG
Clonality Monoclonal
Immunogen Recombinant human PAI
Specificity This antibody recognizes both free and complexed forms of Human PAI-1.
Buffer 0.05M Sodium phosphate, 0.1M Sodium chloride, 1mM EDTA, pH 6.6
State: Purified
State: Liquid purified Ig
Concentration lot specific
Purification >98% pure (SDS-PAGE). Protein A chromatography
Conjugation Unconjugated
Storage Upon receipt, store undiluted (in aliquots) at -20°C or long term (in aliquots) at -70°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name serpin family E member 1
Database Link
Background PAI1 (plasminogen activator inhibitor 1) is originally cloned from human endothelial cell (Pannekoek 1986, Ginsburg 1986) and rat hepatoma cell 3 cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI1 inhibits both tissue type plasminogen activator (tPA) and urokinase type plasminogen activator (uPA). High PAI1 levels are associated with an increased risk of thromboembolic disease while PAI1 deficiency may represent an inherited autosomal recessive bleeding disorder.
Synonyms Serpin E1, PLANH1, Plasminogen Activator Inhibitor 1, PAI-1, PAI
Reference Data
Atlas Protein Categories Cardiovascular diseases, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Complement and coagulation cascades, p53 signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.