CD36 Mouse Monoclonal Antibody [Clone ID: TR9]
Specifications
| Product Data | |
| Clone Name | TR9 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry: 2 µg/ml. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Platelets. |
| Specificity | The antibody TR9 reacts with CD36 (GPIIIb), a 85 kDa integral membrane glycoprotein expressed on platelets, macrophages, endothelial cells, early erythroid cells and megakaryocytes. This antibody cross-blocks binding of FITC-labeled standard antibody OKM5. Anti-CD36 antibodies inhibit adhesive functions (e.g. adherence of infected erythrocytes to target cells). |
| Buffer | Tris Buffered Saline (TBS), pH~8.0 State: Purified State: Liquid purified Ig fraction from Ascites (> 95% pure by SDS-PAGE) Preservative: 15 mM Sodium Azide |
| Concentration | lot specific |
| Purification | Purified by protein-A affinity chromatography. |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C. DO NOT FREEZE! |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | CD36 molecule |
| Database Link | |
| Background | CD36 (fatty acid translocase, FAT) is an 88 kDa ditopic glycosylated protein that belongs to the class B family of scavenger receptors. CD36 is expressed by most resting marginal zone B cells but not by follicular and B1 B cells, and it is rapidly induced on Follicular B cells in vitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells, but modulates both primary and secondary antibody response. Similarly to glucose transporter GLUT4, CD36 is translocated from intracellular pools to the plasma membrane following cell stimulation by insulin. In mouse, CD36 is responsible for gustatory perception of long-chain fatty acids. |
| Synonyms | Glycoprotein IIIb, PAS IV, PAS-4, Thrombospondin receptor, GP3B, GP4 |
| Reference Data | |
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