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DcR2 (TNFRSF10D) Mouse Monoclonal Antibody [Clone ID: TRAIL-R4-01]

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SKU
AM03039AF-N
DcR2 (TNFRSF10D) mouse monoclonal antibody, clone TRAIL-R4-01, Azide Free
Size:
100 ug
Conjugation:
Unconjugated
  $380.00
2 Weeks*
Size
Bulk/Customize

View other "TNFRSF10D or NP_003831.2" antibodies

Specifications
Specifications
Product Data
Clone Name TRAIL-R4-01
Application FC
Recommended Dilution Suitable for use in Flow Cytometry (1-5 µg/ml).
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen TRAIL-R4 (aa 1-210) - hIgGhc fusion protein
Specificity This antibody reacts with TRAIL-R4, a 42 kDa transmembrane protein expressed on various blood cells.
Buffer PBS, pH 7.4 without preservatives
State: Azide Free
State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Concentration lot specific
Purification Protein A affinity chromatography
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid freeze/thaw cycles.
Stability Shelf life: One year from despatch.
Shipping Blue Ice
Gene Name tumor necrosis factor receptor superfamily member 10d
Database Link
Background TRAIL-R4 (CD264, TR4, DcR2, TRUNDD), expressed mainly on CD8+ and NK cells, belongs to receptors of TRAIL, a TNF-like membrane toxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R4, however, contains partially truncated death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by impairment death-inducing signaling complex (DISC) processing. TRAIL-R4 interacts with death receptor 5 (DR5) in the native DISC in a TRAIL-dependent manner and prevents its corecruitment with death receptor 4 (DR4).
Synonyms TNFRSF10D, DCR2, TRAIL-R4, TRUNDD, Decoy receptor 2, TRAIL receptor 4
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.