CD24 Mouse Monoclonal Antibody [Clone ID: SN3]

CAT#: AM03032PU-N

CD24 mouse monoclonal antibody, clone SN3, Purified

Conjugation: Unconjugated APC FITC PE


USD 296.00

2 Weeks*

Size
    • 100 ug

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Other products for "CD24"

Specifications

Product Data
Clone Name SN3
Applications FC, IHC
Recommended Dilution Flow Cytometry.
Immunohistochemistry (frozen sections).
Positive tissue: tonsil.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Glycoproteins purified from human NALM-1 cell line
Specificity The antibody SN3 reacts with CD24, a 35-45 kDa heavily glycosylated cell surface antigen. CD24 is expressed by granulocytes, B lymphocytes and by some activated T cells and T cell malignancies. It is not expressed on human thymocytes.
Formulation PBS, pH 7.4 with 15 mM sodium azide as preservative
State: Purified
State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Concentration lot specific
Purification Protein A affinity chromatography
Conjugation Unconjugated
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Gene Name CD24 molecule
Background CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4; it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid.
Synonyms X62 heat stable antigen, HSA
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.