HLA Class I ABC Mouse Monoclonal Antibody [Clone ID: W6/32]

CAT#: AM03005FC-N

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HLA Class I ABC mouse monoclonal antibody, clone W6/32, FITC



USD 374.00


Availability*
2 Weeks

Size
    • 100 ug


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Specifications

Product Data
Clone Name W6/32
Applications FC
Recommended Dilution Flow Cytometry (1/300 as starting dilution).
Reactivities Bovine, Feline, Human, Primate
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Membrane of Human tonsil cells
Specificity The antibody W6/32 recognizes virtually all nucleated human cells. It is a valuable reagent for analysing variations in HLA class I expression in different disease states e.g. liver disease, muscular dystrophy, inflammatory myopathy and other neuromuscular disorders.
This antibody W6/32 is also suitable as a Positive Control for HLA tissue typing and crossmatching.
Formulation Phosphate buffered saline (PBS), pH~7.4
Label: FITC
State: Liquid purified IgG fraction
Preservative: 15 mM Sodium Azide
Label: Conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC.
Concentration lot specific
Conjugation FITC
Storage Store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Background HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta-2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types.
Synonyms MHC class I ABC, HLA Class 2 ABC
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.