TAC1 Mouse Monoclonal Antibody [Clone ID: SP-DE4-21]
$475.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | SP-DE4-21 |
|---|---|
| Application | ELISA, IF, IHC |
| Recommended Dilution | ELISA: 1/10,000. Immunohistochemistry on Vibratome Sections: 1/500-1/1,000. Immunohistochemistry on Frozen Sections: 1/300 (Ref.2-4). Specimen fixation not in Methanol. |
| Reactivity | Guinea Pig, Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Synthetic Human Substance P. |
| Specificity | The antibody reacts specifically with Substance P. No cross reaction against related Tachykinins (Neurokinin A, Neurokinin B, and Kassinin). |
| Buffer | PBS, pH 7.4 State: Purified State: Lyophilized purified IgG fraction from Cell Culture Supernatant |
| Reconstitution Method | Restore in aqua bidest to 1 mg/ml. |
| Concentration | 1.0 mg/ml (after reconstitution) |
| Purification | Affinity Chromatography on Protein A |
| Conjugation | Unconjugated |
| Storage | Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Ambient |
| Gene Name | tachykinin precursor 1 |
| Database Link | |
| Background | Substance P (SP) is currently thought to be one of the most important neurotransmitters and neurotransmitters in the brain. It is an undecapeptide belonging to the tachykinin family, which consists of excitatory neuropeptides synthesised in neuronal and glial cells of the human central and peripheral nervous system. Substance P, Neurokinin A, Neuropeptide K, and Neuropeptide gamma are all generated by post-translation cleavage of the precursor Protachykinin-1. Substance P forms the major endogenous ligand for Neurokinin 1 Receptor. The pharmacology of Substance P has been associated with a number of neurological and psychiatric disorders, namely nociception, migraine, asthma, nausea, inflammatory bowel syndrome, urinary incontinence, anxiety and depression. It has also been linked to obesity. |
| Synonyms | Substance-P |
| Note | LocusID 6863 (tachykinin precursor contains: substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma). |
| Reference Data | |
| Protein Families | Druggable Genome, Secreted Protein |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.