beta Defensin 3 (DEFB103A) (6-22) Mouse Monoclonal Antibody [Clone ID: L3-18b-E1]
Specifications
| Product Data | |
| Clone Name | L3-18b-E1 |
|---|---|
| Application | ELISA, IHC, R, WB |
| Recommended Dilution | RIA. ELISA. Western Blot (Ref.1). Immunohistochemistry Paraffin Sections: 1/50 (Ref.1). |
| Reactivity | Human, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Synthetic Human beta-Defensin 3 (aa 6-22) |
| Specificity | This antibody detects Human beta-Defensin 3 (aa 6-22), Rat beta-Defensin 3. |
| Buffer | 50 mM TRIS pH 7.4 State: Purified State: Lyophilized purified IgG fraction from Cell Culture Supernatant |
| Reconstitution Method | Restore in aqua bidest to 1 mg/ml. |
| Purification | Protein G Chromatography |
| Conjugation | Unconjugated |
| Storage | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Ambient |
| Gene Name | defensin beta 103A |
| Database Link | |
| Background | Beta Defensin 3 exhibits antimicrobial activity against Gram positive bacteria S.aureus and S.pyogenes, Gram negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. It kills multiresistant S.aureus and vancomycin resistant E.faecium, but it appears to have no significant hemolytic activity. Beta Defensin 3 is highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression is observed in salivary gland, bone marrow, colon, stomach, polyp and larynx, with no expression in small intestine. Expression is induced by infection of bacteria and by interferon gamma. Beta Defensin 3 belongs to the beta defensin family. |
| Synonyms | DEFB103A, DEFB103B, BD3, DEFB3, HBP3, HBD3, DEFB103, Beta-defensin 103, Defensin-like protein, Defensin beta 103 |
| Note | GenID: 55894 and 414325 |
| Reference Data | |
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