FK506 Mouse Monoclonal Antibody [Clone ID: FK1]
Specifications
| Product Data | |
| Clone Name | FK1 |
|---|---|
| Application | ELISA |
| Recommended Dilution | ELISA. |
| Reactivity | Streptomyces tsukubaensis |
| Antibody Host | Mouse |
| Isotype | IgM |
| Clonality | Monoclonal |
| Immunogen | FK-506-BSA conjugate. Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line. |
| Specificity | This antibody clone FK1 detects FK-506, a macrolide with similar but more potent immunosuppressant activity than cyclosporine. |
| Buffer | TRIS buffered saline, pH 8.0 State: Purified State: Liquid purified IgM fraction Preservative: 0.09% Sodium Azide |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Background | FK-506 is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis. FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogenic organ transplantation to reduce organ rejection. Side effects of FK-506 treatment include nephrotoxicity, neurotoxicity, diabetes mellitus and hypertension. |
| Synonyms | Tacrolimus, FK-506 |
| Reference Data | |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.