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Complement C3 (C3) Mouse Monoclonal Antibody [Clone ID: 053A-1149.3.1.4 (1003)]

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SKU
AM01327PU-N
Complement C3 (C3) mouse monoclonal antibody, clone 053A-1149.3.1.4 (1003), Purified
Size:
100 ul
Conjugation:
Unconjugated
  $845.00
5 Days*
Size
Bulk/Customize

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Specifications
Specifications
Product Data
Clone Name 053A-1149.3.1.4 (1003)
Application ELISA, FC, IHC, WB
Recommended Dilution ELISA.
Western blot: 1/5000.
Flow Cytometry.
Immunohistochemistry on Frozen Sections.
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Purified C3d from Human plasma
Specificity This antibody is specific for complement component 3d (C3d), a 33kDa polypeptide fragment generated over the course of complement activation where complement 3 (C3) convertases cleave C3 to C3b, which is further degraded into iC3b and C3dg/C3d.
Buffer Borate buffered saline, pH 8.4
State: Purified
State: Liquid purified Ig fraction
Preservative: 0.09% Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein A
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name complement component 3
Database Link
Background C3d is involved in the regulation of many aspects of the immune response, including antigen processing and presentation. The C3d/antigen complex mediates B cell activation by simultaneously binding antigen-specific surface bound immunoglobulin and CD21, lowering the complement activation threshold. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation.
Synonyms CPAMD1, Complement component 3
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.