TLR2 Mouse Monoclonal Antibody [Clone ID: 11G7]

CAT#: AM01317RP-N

TLR2 mouse monoclonal antibody, clone 11G7, PE

Specifications

Product Data

• Clone Name: 11G7
• Applications: FC
• Recommended Dilution: Immunoprecipitation.
  Flow Cytometry: Use 10 µl of the suggested working dilution to label 1x10⁶ cells in 100 µl. (1/100-1/200).
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity: This antibody recognises the Toll-like receptor 2 (TLR2).
  Antibody 11G7 has been reported to block IL-6 cytokine production in response to ara-lipoarabinomannan (araLAM) and tripalmitoyl cysteinyl lipopeptide (Pam3CSK4) (1). 11G7 does not inhibit the production of cytokines induced by zymosan stimulation.
• Formulation: PBS, pH 7.4
  Label: PE
  State: Lyophilized purified IgG fraction from tissue culture supernatant
  Stabilizer: 1% BSA, 5% Sucrose
  Preservative: 0.09% Sodium Azide
  Label: R. Phycoerythrin (RPE)
• Reconstitution Method: Restore in 1 ml disilled water
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G
• Conjugation: PE
• Storage: Prior to and following reconstitution store undiluted at 2-8°C.
  DO NOT FREEZE!
  This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Gene Name: toll like receptor 2
• Database Link:
  Entrez Gene 7097 Human
  UniProt ID O60603
• Background: TLR2 is a 90kD type 1 transmembrane protein that is primarily expressed by peripheral blood monocytes. TLR2, also known as CD282, is reported to respond to a diverse range of bacterial cell wall components, mediating the innate immune response in co-operation with MD-2.
• Synonyms: Toll-like receptor 2