TLR2 Mouse Monoclonal Antibody [Clone ID: 11G7]
Specifications
| Product Data | |
| Clone Name | 11G7 |
|---|---|
| Application | FC |
| Recommended Dilution | Immunoprecipitation. Flow Cytometry: Use 10 µl of the suggested working dilution to label 1x106 cells in 100 µl. (1/100-1/200). |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Specificity | This antibody recognises the Toll-like receptor 2 (TLR2). Antibody 11G7 has been reported to block IL-6 cytokine production in response to ara-lipoarabinomannan (araLAM) and tripalmitoyl cysteinyl lipopeptide (Pam3CSK4) (1). 11G7 does not inhibit the production of cytokines induced by zymosan stimulation. |
| Buffer | PBS, pH 7.4 Label: PE State: Lyophilized purified IgG fraction from tissue culture supernatant Stabilizer: 1% BSA, 5% Sucrose Preservative: 0.09% Sodium Azide Label: R. Phycoerythrin (RPE) |
| Reconstitution Method | Restore in 1 ml disilled water |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | PE |
| Storage | Prior to and following reconstitution store undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | toll like receptor 2 |
| Database Link | |
| Background | TLR2 is a 90kD type 1 transmembrane protein that is primarily expressed by peripheral blood monocytes. TLR2, also known as CD282, is reported to respond to a diverse range of bacterial cell wall components, mediating the innate immune response in co-operation with MD-2. |
| Synonyms | Toll-like receptor 2 |
| Reference Data | |
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