Ly86 Rat Monoclonal Antibody [Clone ID: MD113]

CAT#: AM01288FC-N

Ly86 rat monoclonal antibody, clone MD113, FITC

Specifications

Product Data

• Clone Name: MD113
• Applications: FC
• Recommended Dilution: Flow cytometry: The typical starting working dilution is 1:50.
  Cannot be used for Western blot.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2b
• Clonality: Monoclonal
• Specificity:
  The monoclonal antibody MD113 reacts with mouse MD-1. The antibody is antagonistic in LPS-induced B-cell proliferation and B7.2 up-regulation.
• Formulation: PBS
  Label: FITC
  State: Liquid 0.2 μm filtered Ig fraction
  Stabilizer: 1.0% bovine serum albumin
  Preservative: 0.02% sodium azide
• Concentration: lot specific
• Purification: Protein G
• Conjugation: FITC
• Storage:

  Store at 2 - 8 °C.
  

• Stability: Shelf life: one year from despatch.

• Gene Name: lymphocyte antigen 86
• Database Link:
  Entrez Gene 17084 Mouse
  UniProt ID O88188
• Background: MD-1 (22-25 kD) is an extracellular protein associated with the extracellular domain of RP105. The latter is a type 1 transmembrane protein with leucine-rich repeats. RP105 is similar to Drosophila Toll. MD-1 associated with RP105 (similar to TLR4/MD-2) appears to be an essential molecule that helps RP105 on B-cells to signal to LPS.
• Synonyms: Lymphocyte antigen 86, MD1