Il17a Rat Monoclonal Antibody [Clone ID: TC11-8H4]
$755.00
5 Days*
Specifications
| Product Data | |
| Clone Name | TC11-8H4 |
|---|---|
| Application | ELISA |
| Recommended Dilution | ELISA. |
| Reactivity | Mouse |
| Antibody Host | Rat |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Recombinant mouse IL-17 expressed in E. coli |
| Specificity | This antibody recognises mouse Interleukin 17. |
| Buffer | Borate buffered saline, pH8.2 State: Purified State: Liquid purified Ig |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store the antibody in aliquots at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | interleukin 17A |
| Database Link | |
| Background | Interleukin 17 is a 32kDa disulfide-linked homodimer consisting of two 136 amino acid chains, which belongs to the IL-17 family (classified as IL-17A to IL-17F), and signals through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction. |
| Synonyms | IL-17A, IL17, IL-17, CTLA8, CTLA-8 |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.