CD88 / C5R1 Rat Monoclonal Antibody [Clone ID: 10/92]
$645.00
5 Days*
Specifications
| Product Data | |
| Clone Name | 10/92 |
|---|---|
| Application | FC, IHC |
| Recommended Dilution | Flow Cytometry: Use 10 µl of 1/50-1/100 diluted antibody to label 1x106 cells in 100 µl. Immunohistochemistry on Frozen Sections. This clone is reported to work in Immunohistochemistry on Paraffin Sections. |
| Reactivity | Mouse |
| Antibody Host | Rat |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | RBL-2H3 transfected cells expressing murine C5aR. Cells from immunised Lou/c rats were fused with cells of the X63-Ag8.653 myeloma cell line. |
| Specificity | This antibody Clone 10/92 recognizes Murine CD88. Clone 10/92 does not block the binding of the C5a to Murine CD88 (See Souri et al. 2003). |
| Buffer | PBS, pH 7.4 containing 0.09% Sodium Azide State: Purified State: Liquid purified IgG fraction |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | complement component 5a receptor 1 |
| Database Link | |
| Background | CD88 is a 45kD G-protein coupled cell surface receptor, which is otherwise known as C5aR. The CD88 molecule functions as a receptor for the complement component C5a, which is a potent proinflammatory molecule and a chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes. |
| Synonyms | C5a-R, C5aR, C5AR1, Complement Component 5a Receptor 1 |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.