ZAP70 Mouse Monoclonal Antibody [Clone ID: SBZAP]
Specifications
| Product Data | |
| Clone Name | SBZAP |
|---|---|
| Recommended Dilution | Flow Cytometry: Membrane permeabilisation is required. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Peptide corresponding to amino acid residues 280-309 of human ZAP-70, conjugated to KLH. |
| Specificity | This antibody recognises human ZAP-70. |
| Buffer | PBS Label: FITC State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide Label: Fluorescein Isothiocyanate Isomer 1 |
| Concentration | lot specific |
| Conjugation | FITC |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | zeta chain of T cell receptor associated protein kinase 70kDa |
| Database Link | |
| Background | ZAP-70 is a 70kDa tyrosine protein kinase which associates with the T-cell receptor (TCR) zeta chain and undergoes phosphorylation following TCR stimulation. ZAP-70 is primarily expressed in T lymphocytes and natural killer cells, where it plays a key role in T-cell receptor (TCR) signalling. Recent studies suggest that ZAP-70 is also expressed in a population of normal immature B-cells and in B-cells from a sub-set of patients with chronic lymphocytic leukaemia. |
| Synonyms | ZAP-70, ZAP 70, SRK |
| Reference Data | |
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