Cardiac Troponin T (TNNT2) Mouse Monoclonal Antibody [Clone ID: BGN/1288/44]
Specifications
| Product Data | |
| Clone Name | BGN/1288/44 |
|---|---|
| Application | ELISA, WB |
| Recommended Dilution | ELISA. Western Blot (1/100). |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | HMW conjugate |
| Specificity | This antibody recognizes Troponin T Cardiac Isoform 1. Under reducing conditions, this antibody reacts with purified cardiac isoform in Western blotting and does not react with the skeletal isoform under the same conditions. |
| Buffer | PBS, pH 7.2 State: Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | troponin T2, cardiac type |
| Database Link | |
| Background | Cardiac Troponin T, a 36kDa protein, is the tropomyosin binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations within the protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the gene undergo alternative splicing that results in many tissue specific isoforms. |
| Synonyms | cTnT, TnTc, TNNT2 |
| Reference Data | |
| Atlas Protein Categories | Cardiovascular diseases, Intracellular Proteins |
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