Thyroglobulin (TG) Mouse Monoclonal Antibody [Clone ID: BGN/6E10]
Specifications
| Product Data | |
| Clone Name | BGN/6E10 |
|---|---|
| Application | ELISA |
| Recommended Dilution | ELISA: This antibody is suitable for use as a Capture antibody in a Sandwich ELISA with BGN/6D7 (BM733) as the Detection antibody. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Purified Native Human Thyreoglobulin. |
| Specificity | Reacts with different epitope to clone BGN/6D7 (BM733) and can be used as the coated antibody in 2 site assay with this clone. |
| Buffer | PBS, pH 7.2 containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction. |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein G. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | thyroglobulin |
| Database Link | |
| Background | Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients. |
| Synonyms | Thyreoglobulin, TGN |
| Reference Data | |
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