KMP-11 Mouse Monoclonal Antibody [Clone ID: L157]

CAT#: AM01169SU-N

KMP-11 mouse monoclonal antibody, clone L157, Ascites

Specifications

Product Data

• Clone Name: L157
• Applications: ELISA, IF, WB
• Recommended Dilution: ELISA: 1/2000.
  Immunoblotting: 1/1000-1/3000.
  Immunofluorescence: 1/500-1/1000.
• Reactivities: Leishmania donovani
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: L. donovani lipophosphoglycan semi purified from epimastigotes.
• Specificity: This antibody recognizes Kinetoplastid Membrane Protein 11 (KMP-11).
  Clone L-157 was originally derived against Leishmania donovani lipophosphoglycan, but found to recognise the tightly associated LPGAP. KMP-11 is found in a wide variety of Kinetoplastid parasites including African trypanosomes, Leishmania and Crithidia.
• Formulation: State: Ascites
  State: Lyophilized Ascites
  Stabilizer: None
  Preservative: None
• Reconstitution Method: Restore with 0.5 ml distilled sterile water.
  Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution.
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C for 6 months or at -20°C long term.
  After reconstitution store the antibody undiluted at 2-8°C for one month
  or (in aliquots) at -20°C long term.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  UniProt ID Q36736
• Background:
  Kinetoplastid Membrane Protein-11 (KMP-11), previously known as the lipophosphoglycan-associated protein (LPGAP), is an 11 kDa membrane protein.
  KMP11 may be involved in the regulation of the cytoskeleton through interaction with the subpellicular microtubules. It may be involved in parasite mobility and attachment to the surface of the host cell. It strongly stimulates T-cell proliferation and it is thought to play a role in the immunology of leishmaniasis.
• Synonyms: KMP11, LPGAP