Ki67 (MKI67) Mouse Monoclonal Antibody [Clone ID: Ki-67]
$305.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | Ki-67 |
|---|---|
| Application | FC, IF, WB |
| Recommended Dilution | Flow cytometry: Recommended dilution: 1-5 µg/ml. Intracellular staining. Immunocytochemistry: Paraformaldehyde fixation; recommended antibody concentration 1 μg/ml. |
| Reactivity | Bovine, Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Nuclei of the Hodgkin lymphoma cell line L428 |
| Specificity | This antibody recognizes Ki-67 antigen, a non-histone nuclear protein expressed exclusively in proliferating cells. |
| Buffer | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 State: Purified State: Liquid Ig fraction |
| Concentration | lot specific |
| Purification | Protein-A affinity chromatography (> 95% pure by SDS-PAGE) |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C. DO NOT FREEZE! |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | marker of proliferation Ki-67 |
| Database Link | |
| Background | Ki-67 is a highly protease-sensitive nuclear protein expressed in two isoforms (345 kDa and 395 kDa), both of which are identified by the antibody clone Ki-67. The Ki-67 antigen is essential for cell proliferation and its expression is restricted to the cycling cells. It is detected in G1, S, G2 and M phase, whereas it is absent in cells which are in G0 phase and it is not associated with DNA repair processes. Ki-67 thus represents an important tool for detection of proliferating cells, which is of great importance in tumor diagnostics and is commonly used as a prognostic factor in cancer studies. |
| Synonyms | Ki67 antigen, MKI67, Proliferation marker |
| Reference Data | |
| Atlas Protein Categories | ADC Targets, Intracellular Proteins |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.