FeLV envelope glycoprotein TM p15E Mouse Monoclonal Antibody [Clone ID: PF6J-2A1]
Specifications
| Product Data | |
| Clone Name | PF6J-2A1 |
|---|---|
| Application | IHC, IP, WB |
| Recommended Dilution | Immunohistochemistry on paraffin sections. Immunoprecipitation. Western Blot: 1:2,000; detects band/s of approximately 15kDa and 20kDa under reducing conditions. |
| Reactivity | Feline Leukemia Virus |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Specificity | This antibody recognises an epitope within the amino-terminal domain of both the 20kDa full-length (including intracellular sequence), and the 15kDa truncated forms, of feline leukaemia virus (FeLV) p15e transmembrane envelope protein. |
| Buffer | PBS, pH7.2 containing 0.05% Sodium Azide State: Purified State: Liquid purified Ig |
| Concentration | lot specific |
| Purification | Affinity chromatography on Protein A |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Database Link | |
| Background | Persistent infection of cats with the oncoretrovirus FeLV can result in the non-neoplastic condition known as FeLV-associated enteritis (FAE). Studies have shown strong expression of the major FeLV proteins p15e and gp70 in intestinal crypt epithelial cells of cats with FAE, compared to FeLV-positive cats without intestinal alterations, thereby suggesting a pathogenic role for these envelope proteins/precursors in FAE. |
| Synonyms | Feline leukemia virus env, gp70, p15E |
| Reference Data | |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |