TNFRSF4 Mouse Monoclonal Antibody [Clone ID: 7D6]
Specifications
| Product Data | |
| Clone Name | 7D6 |
|---|---|
| Application | FC, WB |
| Recommended Dilution | Flow Cytometry: 1/5; use 10µl of the suggested working dilution to label 1x10e6 cells in 100µl. |
| Reactivity | Feline, Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | CHO-derived feline CD134-Fc fusion protein. |
| Specificity | This antibody recognizes Feline CD134, otherwise known as OX40. The antibody weakly reacts with Human. It does not react with Mouse. |
| Buffer | Phosphate buffered saline pH 7.4 containing 0.09% Sodium Azide, 1% BSA Label: FITC State: Liquid purified Ig fraction Label: Fluorescein Isothiocyanate Isomer 1 |
| Concentration | lot specific |
| Purification | Affinity Chomatography on Protein G |
| Conjugation | FITC |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | tumor necrosis factor receptor superfamily member 4 |
| Database Link | |
| Background | CD134 is a 43kDa type I membrane protein and member of the tumor necrosis factor receptor superfamily, expressed predominantly by CD4+ activated T cells, and a key regulator of T cell-dependent immune responses CD134 has been identified as the receptor for the OX40 ligand, CD252, expressed by activated B cells, acting as a co-stimulatory signal for the stimulation and secretion of immunoglobulins. CD134 has also been identified as a binding receptor for Feline Immunodeficiency Virus (FIV), acting along with CXC chemokine receptor 4 (CXCR4) to facilitate the entry of the virus into CD4+ primary target cells. |
| Synonyms | TNFRSF4, TXGP1L, ACT35 antigen, OX40L receptor |
| Reference Data | |
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