Angiotensinogen (AGT) Mouse Monoclonal Antibody [Clone ID: BGN/0856/21 (08/56a/A2.21)]

CAT#: AM01016PU-N

Angiotensinogen (AGT) mouse monoclonal antibody, clone BGN/0856/21 (08/56a/A2.21), Purified

Specifications

Product Data

• Clone Name: BGN/0856/21 (08/56a/A2.21)
• Applications: ELISA
• Recommended Dilution: ELISA (1/10-1/100).
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic peptide representing Angiotensin II, conjugated to Rabbit Albumin.
• Specificity: This antibody recognizes Angiotensin II and also Angiotensin I and III in ELISA.
  Incomplete mapping indicates the site of reactivity to be Val-Tyr-Ile-His-Pro[AI/II(3-8)], a conserved region of all angiotensin molecules.
• Formulation: PBS buffer, pH 7.2 containing 0.09% Sodium Azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: angiotensinogen
• Database Link:
  Entrez Gene 183 Human
  UniProt ID P01019
• Background: Angiotensin-I is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia.
• Synonyms: Angiotensin-2, Angiotensin-II, ANG2, ANG-2, ANG-II