Ferritin (heavy and light chain) Mouse Monoclonal Antibody [Clone ID: 057-10030]
SKU
AM00839PU-N
Ferritin (heavy and light chain) mouse monoclonal antibody, clone 057-10030, Purified
$615.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | 057-10030 |
|---|---|
| Application | ELISA |
| Recommended Dilution | ELISA. Recommended Pairs for Sandwich Immunoassay Capture/Detection: AM00839PU-N / AM00837PU-N AM00839PU-N / AM00840PU-N AM00839PU-N / AM00841PU-N AM00839PU-N / AM00838PU-N |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Ferritin isolated from human liver |
| Specificity | This antibody reacts to Ferritin. |
| Buffer | 10mM Phosphate, pH 7.4 containing 150mM Sodium Chloride and 0.09% Sodium Azide State: Purified State: Liquid purified Ig fraction (>90% pure by SDS-PAGE). |
| Concentration | lot specific |
| Purification | Protein A Chromatography. Product is 0.2 µm filtered. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one week or (in aliquots) at -40°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Background | Ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis by sequestering and storing iron in a non-toxic and soluble form. It forms a holoenzyme of ~450 kDa, consisting of 24 subunits of two types, H (heavy; 21 kDa) and L (light; 19 kDa), and is capable of storing up to 4,500 atoms of ferric iron. Depending on the tissue type and physiological status of the cell, the ratio of H to L subunits in ferritin can vary widely. Ferritin is found in the liver, spleen, kidney and heart, with smaller amounts being found in blood. Serum ferritin levels serve as an indicator of the amount of iron stored in the body. Serum ferritin is the most sensitive test for anaemia, and is also used as a marker for restless leg syndrome, hemochromatosis and porphyria. As ferritin is an acute-phase reactant, it is often elevated during infection. Defects in ferritin proteins are associated with several neurodegenerative diseases. |
| Synonyms | FTH, FTL, Ferritin H subunit, Ferritin L subunit |
| Reference Data | |
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.