alpha 1 Fetoprotein (AFP) Mouse Monoclonal Antibody [Clone ID: 131-12210 (TB-4B2-10)]

CAT#: AM00787PU-N

alpha 1 Fetoprotein (AFP) mouse monoclonal antibody, clone 131-12210 (TB-4B2-10), Purified

Specifications

Product Data

• Clone Name: 131-12210 (TB-4B2-10)
• Applications: ELISA, IHC
• Recommended Dilution: Immunohistochemistry.
  ELISA.
  Recommended pair for sandwich immunoassay:
  Capture: AM00787PU-N
  Detection: AM00786PU-N
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: AFP prepared from human placenta
• Specificity: This antibody recognizes Alpha Fetoprotein (AFP).
• Formulation: 10mM Phosphate, pH 7.2 containing 150mM Sodium Chloride
  State: Purified
  State: Liquid purified IgG fraction (0.2µm filtered)
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: alpha fetoprotein
• Database Link:
  Entrez Gene 174 Human
  UniProt ID P02771
• Background: Alpha fetoprotein is a 68kD plasma protein found in fetuses over four weeks old, produced by the yolk sac and the fetal liver, with the highest concentration reached during the 12th to 16th week of gestation. It binds and transports various ligands such as bilirubin, fatty acids, steroids, heavy metals and various drugs. After birth, plasma levels drop to trace amounts in healthy adults.
  Elevated AFP levels are indicative of certain cancers, particularly hepatocellular carcinoma, cancer of the testes or ovaries or a malignant teratoma. During pregnancy increased levels of AFP may indicate neural tube defects such as spina bifida, while decreased levels could indicate Down’s syndrome.
• Synonyms: Alpha-1-fetoprotein, Alpha-fetoglobulin, HPAFP
• Note: Centrifuge before opening to ensure complete recovery of vial contents.