Cortisol Mouse Monoclonal Antibody [Clone ID: CORT-1]
$790.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | CORT-1 |
|---|---|
| Application | ELISA |
| Recommended Dilution | Can be used in competitive assay of Cortisol. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Cortisol-3 (CMO)-BSA. |
| Specificity | This antibody reacts to Cortisol-BSA conjugate and free cortisol. There is no cross-reactivity with BSA. Cross-reactivity: (50% displacement of cortisol-3-125-Iodine) Cortisol: 100% Corticosterone: 20% 17-Hydroxyprogesterone: 0% |
| Buffer | PBS, pH 7.4 containing 0.09% Sodium Azide as preservative State: Purified State: Liquid purified IgG fraction (>/= 95% pure). |
| Concentration | lot specific |
| Purification | Protein G Sepharose Chromatography (Source: Ascites). Purity is tested by electrophoresis |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Background | Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism. |
| Synonyms | Hydrocortisone |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.