CD1B Mouse Monoclonal Antibody [Clone ID: 100-1A5]
$525.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | 100-1A5 |
|---|---|
| Application | IF, IHC |
| Recommended Dilution | Flow Cytometry (1). Immunofluorescence. Immunohistochemistry on Frozen Sections Positive Control: Human lymphocytes. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgM |
| Clonality | Monoclonal |
| Immunogen | Stimulated Human leucocytes. Splenocytes were fused with mouse myeloma NS1 cells. |
| Specificity | 100-1A5 binds with CD1b which is a 45 kD membrane glycoprotein expressed together with beta-2 Microglobulin. This antibody reacts with cortical thymocytes, Langerhans cells interdigitating cells and with pyramidal cells in the brain. It can be applied for characterization of leukemia's and lymphomas. Cellular Localization: Cell membrane and cytoplasm. |
| Buffer | PBS State: Purified State: Liquid purified Ig fraction Preservative: 0.05% Sodium Azide |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C |
| Stability | Shelf life: One year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 45 kDa |
| Gene Name | CD1b molecule |
| Database Link | |
| Background | CD1b which is associated with β2 microglobulin (1) is expressed on cortical thymocytes (moderate), Langerhans cells, interdigitating cells and brain pyramidal cells (1). It is up-regulated in peripheral neuropathy and inflammatory diseases (2,3). CD1b is the member of CD1 family. At least five CD1 genes (CD1a, b, c, d, and e) are identified (1). Unlike other members in CD1 family which have multiple splicing patterns, CD1b only revealed a single membrane RNA product (1). CD1 proteins including CD1b have been demonstrated to restrict T-cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation (4) |
| Synonyms | CD1; CD1A; MGC125990; MGC125991; R1 |
| Reference Data | |
| Atlas Protein Categories | CD Markers, Membrane Proteins |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.