p75 NGF Receptor (NGFR) (1-160) Mouse Monoclonal Antibody [Clone ID: NGFR5]

CAT#: AM00235PU-N

p75 NGF Receptor (NGFR) (1-160) mouse monoclonal antibody, clone NGFR5, Purified

Conjugation: Unconjugated Biotin


USD 245.00

2 Weeks*

Size
    • 100 ug

Product Images

Other products for "NGFR"

Specifications

Product Data
Clone Name NGFR5
Applications FC, IF, IHC, IP, WB
Recommended Dilution Flow Cytometry.
Immunoprecipitation.
Western blot.
Immunohistochemistry on Paraffin Sections: 1-2 μg/ml (Heat-mediated antigen retrieval required).
Positive Control: melanoma tissue. 
Immunocytochemistry.
Reactivities Feline, Ferret, Human, Monkey, Rabbit
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Purified CD271 protein isolated from Human melanoma cell line A875
Specificity This antibody recognizes CD271/NGFR, a transmembrane glycoprotein of the TNFR superfamily.
The epitope is localized within amino acids 1-160.
Cellular Localization: Cell Surface, Cytoplasmic.
Formulation PBS, pH~7.4
State: Purified
State: Liquid purified Ig fraction from Cell Culture Supernatant (> 95% pure by SDS-PAGE)
Preservative: 15 mM Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein A
Conjugation Unconjugated
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Predicted Protein Size 75 kDa
Background CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
Synonyms TNFRSF16
Reference Data

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.