Phosphotyrosine (incl. pos. control) Mouse Monoclonal Antibody [Clone ID: 2C8]
$620.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | 2C8 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry. |
| Reactivity | Canine, Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Synthetic phosphopeptide conjugated to KLH |
| Specificity | Mab PTYR-2C8 recognizes a broad range of tyrosine--phosphorylated proteins in crude cell extracts and may therefore be particularly well-suited for the detection/screening of tyrosine phosphorylated proteins. |
| Buffer | PBS/0.09% Na-Azide/PEG and Sucrose Label: FITC State: Liquid purified IgG |
| Concentration | lot specific |
| Purification | Size exclusion chromatography |
| Conjugation | FITC |
| Storage | Store the antibody at -80°C. Avoid repeated freezing and thawing. Thaw aliquots at 37°C. Thawed aliquots may be stored at 4°C up to 3 months. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Background | Phosphorylation and dephosphorylation of cellular proteins are central steps in transducing extracellular signals to the cell nucleus. Phosphorylated epitopes may serve as docking sites for the assembly of protein complexes or may alter the 3-dimensional protein structure thus modulating enzymatic activity or the ability to undergo protein-protein-interactions. Modification of proteins on tyrosine residues is mediated by protein tyrosine kinases. Tyrosine phosphorylation may alter the biological activity or mediate the assembly of protein complexes via interaction of phosphotyrosine residues with SH2 or PID domains. |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.