GSK3 beta (GSK3B) pSer9 (incl. pos. control) Mouse Monoclonal Antibody [Clone ID: 3A8]
Specifications
| Product Data | |
| Clone Name | 3A8 |
|---|---|
| Application | ELISA, WB |
| Recommended Dilution | Western Blot: 0.5 µg/ml for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubation buffer. ELISA: 0.05 µg/ml. |
| Reactivity | Canine, Human, Mouse |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Synthetic phosphopeptide conjugated to KLH. |
| Specificity | This antibody specifically recognizes GSK3beta phosphorylated at Ser 9 at 46 kDa. |
| Buffer | PBS/0.09% Na-Azide/PEG and Sucrose Label: Biotin State: Liquid purified IgG |
| Concentration | lot specific |
| Purification | Size exclusion chromatography |
| Conjugation | Biotin |
| Storage | Store the antibody (aliquote in liquid nitrogen) at -80°C. Avoid repeated freezing and thawing. Thaw aliquots at 37°C. Thawed aliquots may be stored at 4°C up to 3 months. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | glycogen synthase kinase 3 beta |
| Database Link | |
| Background | Glycogen Synthase Kinase 3 beta (GSK3beta) is a serine/threonine kinase that is acting independently of most signal transduction pathways. The activity of GSK3beta can be modulated by phosphorylation of Ser9 and Tyr215 in the activation loop. GSK3beta plays a crucial role in phosphorylation of beta-catenin and thus is an important kinase involved in the regulation of beta-catenin/wnt-signaling. |
| Synonyms | GSK-3 beta, Glycogen synthase kinase-3 beta, GSK3B |
| Reference Data | |
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