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Amyloid beta (1-40/42) Mouse Monoclonal Antibody [Clone ID: 9F1]

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SKU
AM00002FC-N
Amyloid beta (1-40/42) mouse monoclonal antibody, clone 9F1, FITC
Size:
100 ug
Conjugation:
FITC Biotin Unconjugated
  $620.00
2 Weeks*
Size
Bulk/Customize
Specifications
Specifications
Product Data
Clone Name 9F1
Application IF
Recommended Dilution Immunocytochemistry: 1-10 µg/ml.
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen KLH conjugated C-terminal peptide of Amyloid beta A4 (1-40) and beta A4 (1-42).
Specificity This antibody interacts with the C-termini of both beta-Amyloid (1-40) and (1-42).
Buffer PBS containing 0.09% Sodium Azide, PEG and Sucrose.
Label: FITC
State: Liquid purified IgG fraction.
Concentration lot specific
Purification Size Exclusion Chromatography.
Conjugation FITC
Storage Store the antibody (aliquote in liquid nitrogen) at -80°C.
Avoid repeated freezing and thawing.
Thaw aliquots at 37°C. Thawed aliquots may be stored at 4°C up to 3 months.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Background The beta-amyloid peptide (beta A4), proteolytically released from the amyloid precursor protein (APP), is the principal component of senile plaques in Alzheimer's disease. Cleavage of APP by alpha-secretase or alternatively by beta-secretase leads to generation and extracellular release of soluble APP peptides, S-APP-alpha and S-APP-beta, respectively, and the retention of corresponding membrane-anchored C-terminal fragments, C83 and C99. Subsequent processing of C83 by gamma-secretase yields P3 peptides. This is the major secretory pathway and is nonamyloidogenic. Alternatively, presenilin/nicastrin-mediated gamma-secretase processing of C99 releases the amyloid beta proteins, amyloid-beta 40 (Abeta40) and amyloid-beta 42 (Abeta42), major components of amyloid plaques, and the cytotoxic C-terminal fragments, gamma-CTF(50), gamma-CTF(57) and gamma-CTF(59).
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.