Posts for 7/2022


ACE2: A predictor of infectability in SARS-Cov-2

Jul 13, 2022

Angiotensin converting enzyme 2 (ACE-2), is a single-pass type I membrane protein and a zinc metalloprotease of the ACE family. ACE2 encodes for a protein that catalyzes the cleavage of angiotensin I into angiotensin 1-9 and angiotensin II into vasodilator angiotensin 1-7. Human ACE-2 protein consists of 805 amino acids, including a N-terminal signal peptide, a single catalytic domain, a junctional segment of the collectrin domain, a peptidase cleavage site, a TM domain, and...

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Human IL6: A Pleiotropic Inflammatory Cytokine

Jul 11, 2022

Interleukin 6 (IL-6) is a pleiotropic cytokine. It plays important role in inflammation disorders, autoimmune diseases, obesity, and cancer. Levels of IL-6 in human blood are very low under normal conditions, but the levels can increase thousands-fold in inflammatory states. Thus, monitoring IL-6 levels can help in diagnosing and preventing infectious diseases. IL-6 Signaling Pathway IL-6 has both pro-and anti-inflammatory functions that are mediated by the soluble form of IL-6...

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