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MDA5 Pathway

MDA5, encoded by gene IFIH1, is a member of the RLR family. It is a pattern-recognition receptor that recognizes viral RNA and induces type 1 interferon response. Recent studies have shown that MDA5 recognizes cellular and viral RNAs through its interactions with multiple genes. Find out which genes are involved in this MDA5 pathway here »

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ACE2: A predictor of infectability in SARS-Cov-2

Angiotensin-converting enzyme 2 (ACE-2), is a single-pass type I membrane protein and a zinc metalloprotease of the ACE family. ACE2 encodes for a protein that catalyzes the cleavage of angiotensin I into angiotensin 1-9 and angiotensin II into vasodilator angiotensin 1-7. Read about its role in SARS-Cov-2 in the blog here »

IL6: A Pleiotropic Inflammatory Cytokine

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