A new subtype of bone sarcoma defined by BCOR-CCNB3 gene fusion
Nature Genetics 44, 461-466 doi:10.1038/ng.1107
[Testis mRNA]
Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)
PNAS, Feb 2012; 109: 2989 - 2994.
[Primary Tissue and DNA Samples]
Circulating Adiponectin Is Inversely Associated with Risk of Thyroid Cancer: In Vivo and in Vitro Studies
J. Clin. Endocrinol. Metab., Dec 2011; 96: E2023 - E2028.
[four normal thyroid tissue specimens
]
QKI-Mediated Alternative Splicing of the Histone Variant MacroH2A1 Regulates Cancer Cell Proliferation
Mol. Cell. Biol., Oct 2011; 31: 4244 - 4255.
[Breast Tissue RNA]
Comprehensive Human Cancer and Normal Tissue Products
TissueFocus™ Search Tool allows you to search over 30,000 total RNA, genomic DNA, protein lysates, FFPE and frozen sections from human tissue samples. Case-matched tumor and normal samples are available
Tissue total RNA and genomic DNA Samples were derived from our high quality frozen tissues after rigorous QC testing. Agilent Bioanalyzer 28S/18S ratio, Electropherogram, A260/A280 ratio and PCR images available upon request. Samples are offered in 5 ug aliquots.
Tissue Protein Lysate Protein lysates were generated using a Modified RIPA buffer (no SDS) in the presence of protease and phosphatase inhibitors. Protein quantification is performed using the BCA Protein Assay. Samples are offered in 150 ug aliquots.
Tissue Sections Frozen and FFPE tissue sections can be used for applications such as IHC, ISH, LCM and RNA/DNA/Protein extractions. Each section is freshly cut onto a SuperFrost positively charged glass slide, and offered as a set of 5 slides (each 5 micron thickness).
TissueFocus™ Block available in formalin-fixed, paraffin embedded OR frozen, OCT-embedded formats
OriGene’s comprehensive tissue products provide researchers ready-to-use tools for their studies in biomarker discovery and validation, cancer drug target identification and validation, companion diagnostic assay development, and personalized medicine for the cancer patient. Tissues are banked under strict collection protocols and undergo rigorous quality control to ensure each source block’s unparalleled quality.
Collected from major US institutions under strict IRB and ethical consenting practices
Maintained in a monitored environment and bar-coded for tracking purposes
Each tissue source block includes following clinical information
Abstracted pathology report
Tissue of origin / site of finding
Disease staging
Digital H&E image
Donor’s basic demographic information
Learn more about the quality control of human tissue products
OriGene has developed comprehensive human cancer and normal tissue products from its biorepository of over 140,000 high quality human tissues.
