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OriGene cDNA clone collection in recent publications
The E3 ubiquitin ligase RNF135 regulates the tumorigenesis activity of tongue cancer SCC25 cells Cancer Med 2016 [Ubiquitin-GFC]

Pathological a-synuclein transmission initiated by binding lymphocyte-activation gene 3 Science 2016 [transmembrane]

Mmu-miR-1894-3p Inhibits Cell Proliferation and Migration of Breast Cancer Cells by Targeting Trim46 Int J Mol Sci Apr 2016 []

WDFY1 mediates TLR3/4 signaling by recruiting TRIF EMBO Rep. Apr 2015 [10,000 clones]


Human apolipoprotein E is required for Infectivity and Production of Hepatitis C Virus in Cell Culture Kyung-Soo Chang, Jieyun Jiang, Zhaohui Cai, and Guangxiang Luo JVirol. 2007 Dec;81(24):13783-93 [APOE]

The nuclear RhoA-exchange factor Net1 interacts with proteins of the Dlg family, affects their localization and influences their tumor suppressor activity PaulAGarcia-Mata R, Dubash AD, Sharek L, Carr HS, Frost JA, Burridge K. Mol Cell Biol. 2007 Dec;27(24):8683-97 [NET1]

Differential expression of novel tyrosine kinase substrates during breast cancer development Yunhao Chen, Lee Yee Choong, Qingsong Lin, Robin Philps, Chee Hong Wong, Boon Keong Ang, Yee Ling Tan, Marie Chiew Shia Loh, Choy Leong Hew, Nilesh Shah, Brian J Druker, Poh Kuan Chong, and Yoon Pin Lim Mol Cell Proteomics. 2007 Dec;6(12):2072-87 [NSFL1C]

Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome Paul A. Watkins, Dony Maiguel, Zhenzhen Jia, and Jonathan Pevsner J Lipid Res., Dec 2007 48: 2738-50 [ACSF2]

Down-regulation of Platelet-Derived Growth Factor-D Inhibits Cell Growth and Angiogenesis through Inactivation of Notch-1 and Nuclear Factor- B Signaling Zhiwei Wang, Dejuan Kong, Sanjeev Banerjee, Yiwei Li, N. Volkan Adsay, James Abbruzzese, and Fazlul H. Sarkar Cancer Res., Dec 2007; 67: 11377 - 11385. [PDGF-D]

Cartilage oligomeric matrix protein (COMP) protects cells against death by elevating members of the IAP family of survival proteins Viktoria Gagarina, Alyssa L. Carlberg, Lucilia Pereira-Mouries, and David J. Hall J. Biol. Chem., Nov 2007; 10.1074. [COMP]

The Energy Sensor AMP-activated Protein Kinase Directly Regulates the Mammalian FOXO3 Transcription Factor. Eric L. Greer, Philip R. Oskoui, Max R. Banko, Jay M. Maniar, Melanie P. Gygi, Steven P. Gygi, and Anne Brunet. J. Biol. Chem., Oct 2007; 282: 30107 - 30119. [AMPKalpha2]

Down-regulation of Forkhead Box M1 Transcription Factor Leads to the Inhibition of Invasion and Angiogenesis of Pancreatic Cancer Cells Zhiwei Wang, Sanjeev Banerjee, Dejuan Kong, Yiwei Li, and Fazlul H. Sarkar Cancer Res., Sep 2007; 67: 8293 - 8300. [FoxM1]

Chemotherapeutic stress selectively activates NF-{kappa}B dependent Akt and VEGF expression in liver cancer derived endothelial cells. Meng F, Henson R, Patel T. Am J Physiol Cell Physiol. 2007 Aug;293(2):C749-60. [NFKB1, NFKBIA]

Artificial Sweeteners and Salts Producing a Metallic Taste Sensation Activate TRPV1 Receptors. Celine E Riera, Horst Vogel, Sidney A Simon, and Johannes le Coutre Am J Physiol Regul Integr Comp Physiol. 2007 Aug;293(2):R626-34. [TRPA1, TRPM8]

Estrogen induces expression of BCAS3, a novel estrogen receptor-alpha coactivator, through PELP1. Anupama E Gururaj, Shaohua Peng, Ratna K Vadlamudi, and Rakesh Kumar
Mol Endocrinol. 2007 Aug;21(8):1847-60. [BCAS3]

Molecular Interaction of a Potent Nonpeptide Agonist with the Chemokine Receptor CCR8. PC Jensen, R Nygaard, S Thiele, A Elder, G Zhu, R Kolbeck, S Ghosh, TW Schwartz, and MM Rosenkilde Mol Pharmacol. 2007 Aug;72(2):327-40. [CCR3, CCR4, CCR6, CCR9, CCR10 and CCRL1]

Breast cancer antiestrogen resistance-3 expression regulates breast cancer cell migration through promotion of p130Cas membrane localization and membrane ruffling. RS Schrecengost, RB Riggins, KS Thomas, MS Guerrero, and AH Bouton Cancer Res. 2007 Jul 1;67(13):6174-82.  [BCAR3]

Oxyntomodulin differentially affects Glucagon-Like Peptide-1 receptor beta-arrestin recruitment and signaling through G-alpha-s. Rasmus Jorgensen, Valentina Kubale, Milka Vrecl, Thue W Schwartz, and Christian E Elling J Pharmacol Exp Ther. 2007 Jul;322(1):148-54. [ARRB1]

Serotonin Inhibits Neuronal Excitability by Activating Two-pore Domain K+ Channels in the Entorhinal Cortex. Pan-Yue Deng, Shree Kanta Poudel, Lalida Rojanathammanee, James E Porter, and Saobo Lei Mol Pharmacol. 2007 Jul;72(1):208-18. [KCNK1]

Hepatocyte nuclear factor-4{alpha} regulates the human organic anion transporter 1 gene in the kidney. Ken Ogasawara, Tomohiro Terada, Jun-Ichi Asaka, Toshiya Katsura, and Ken-Ichi Inui Am J Physiol Renal Physiol. 2007 Jun;292(6):F1819-26. [HNF4A]

Proteomic Analysis Identifies Oxidative Stress Induction by Adaphostin. Luke H Stockwin, Maja A Bumke, Sherry X Yu, Simon P Webb, Jack R Collins, Melinda G Hollingshead, and Dianne L Newton Clin Cancer Res. 2007 Jun 15;13(12):3667-3681 [SOD1]

Calcium inhibition and calcium potentiation of orai1, orai2 and orai3 calcium-release-activated calcium channels. Wayne I Dehaven, Jeremy T Smyth, Rebecca R Boyles, and James W Putney Jr J Biol Chem. 2007 Jun 15;282(24):17548-56. [TMEM142A, TMEM142B, TMEM142C]

ELMOD2 is an Arl2 GTPase-activating protein that also acts on arfs. J Bradford Bowzard, Dongmei Cheng, Junmin Peng, and Richard A Kahn J Biol Chem. 2007 Jun 15;282(24):17568-80. [RBED1]

A Previously Unrecognized Protein-Protein Interaction between TWEAK and CD163: Potential Biological Implications. LC Bover, M Cardo-Vila, A Kuniyasu, J Sun, R Rangel, M Takeya, BB Aggarwal, W Arap, and R Pasqualini J Immunol. 2007 Jun 15;178(12):8183-94 [CD163, TNFRSF12A, CD5]

Identification of residues in the Hendra virus G glycoprotein critical for receptor binding.
Kimberly A Bishop, Tzanko S Stantchev, Andrew C Hickey, Dimple Khetawat, Katharine N Bossart, Valery Krasnoperov, Parkash Gill, Yan-Ru Feng, Lemin Wang, Bryan T Eaton, Lin-Fa Wang, and Christopher C Broder J Virol. 2007 Jun;81(11):5893-901. [EFNB2]

Multiple Translational Isoforms Give Functional Specificity to Serum- and Glucocorticoid-induced Kinase 1. Maria Francisca Arteaga, Diego Alvarez, Jose A Alvarez, and Cecilia M Canessa Mol Biol Cell. 2007 Jun;18(6):2072-80. [SGK1, FOXO3]

Adrenal Transcription Regulatory Genes Modulated by Angiotensin II and Their Role in Steroidogenesis Damian Gaston Romero, Silvia Rilli, Maria W Plonczynski, Licy Lorena Yanes, Ming Yi Zhou, Elise P. Gomez-Sanchez, Celso E Gomez-Sanchez.  Physiol Genomics. 2007 Jun 19;30(1):26-34. [NR4A3]

GATA3 upregulation associated with surface expression of CD294/CRTH2: a unique feature of human Th cells Umberto De Fanis, Francesca Mori, Rebecca J. Kurnat, Won Kyung Lee, Maria Bova, N. Franklin Adkinson, Jr, Vincenzo Casolaro Blood. 2007 May 15;109(10):4343-50.  [PPIA]

Interaction of hydroxylated collagen IV with the von Hippel-Lindau tumor suppressor.
Alexandra Grosfeld, Ineke P Stolze, Matthew E Cockman, Christopher W Pugh, Mariola Edelmann, Benedikt Kessler, Alex N Bullock, Peter J Ratcliffe, and Norma Masson J Biol Chem. 2007 May 4;282(18):13264-9. [COL1A1]

v-SNARE cellubrevin is required for basolateral sorting of AP-1B-dependent cargo in polarized epithelial cells. Fields IC, Shteyn E, Pypaert M, Proux-Gillardeaux V, Kang RS, Galli T, Folsch H.
J Cell Biol. 2007 May 7;177(3):477-88. [VAMP2]

Rotavirus NSP1 Inhibits Expression of Type I Interferon by Antagonizing the Function of Interferon Regulatory Factors IRF3, IRF5, and IRF7. Mario Barro and John T Patton
J Virol. 2007 May;81(9):4473-81. [IRF5]

Small-molecule synergist of the Wnt/{beta}-catenin signaling pathway. Qisheng Zhang, Michael B Major, Shinichi Takanashi, Nathan D Camp, Naoyuki Nishiya, Eric C Peters, Mark H Ginsberg, Peter G Schultz, Randall T Moon, and Sheng Ding Proc Natl Acad Sci U S A. 2007 May 1;104(18):7444-8.[ARFGAP1, ARFIP1]

The second extracellular loop of CCR5 contains the dominant epitopes for highly potent anti-human immunodeficiency virus monoclonal antibodies. Jun Zhang, Eileen Rao, Marianna Dioszegi, Rama Kondru, Andre Derosier, Eva Chan, Stephan Schwoerer, Nick Cammack, Michael Brandt, Surya Sankuratri, and Changhua Ji Antimicrob Agents Chemother. 2007 Apr;51(4):1386-97. [CCR5]

Peroxisome Proliferator-Activated Receptor {gamma}-Independent Suppression of Androgen Receptor Expression by Troglitazone Mechanism and Pharmacologic Exploitation. Yang CC, Wang YC, Wei S, Lin LF, Chen CS, Lee CC, Lin CC, Chen CS. Cancer Res. 2007 Apr 1;67(7):3229-38. [SP1]

Selective down-regulation of glioma-associated oncogene 2 inhibits the proliferation of hepatocellular carcinoma cells Y Kim, JW Yoon, X Xiao, NM Dean, BP Monia, and EG Marcusson
Cancer Res. 2007 Apr 15;67(8):3583-93. [SMO]

Phospholipase D2-derived phosphatidic acid binds to and activates ribosomal p70 S6 kinase independently of mTOR. Nicholas Lehman, Bill Ledford, Mauricio Di Fulvio, Kathleen Frondorf, Linda C McPhorigeneail, and Julian Gomez-Cambronero FASEB J. 2007 Apr;21(4):1075-87.  [FRAP1]

Single-stranded DNA-binding proteins regulate the abundance of LIM domain and LIM domain-binding proteins. Z Xu, X Meng, Y Cai, H Liang, L Nagarajan, and SJ Brandt
Genes Dev. 2007 Apr 15;21(8):942-55. [RNF12]

Relocalization of STIM1 for activation of store-operated Ca2+ entry is determined by the depletion of subplasma membrane endoplasmic reticulum Ca2+ store.
Hwei Ling Ong, Xibao Liu, Krasimira Tsaneva-Atanasova, Brij B Singh, Bidhan C Bandyopadhyay, William D Swaim, James T Russell, Ramanujan S Hegde, Arthur Sherman, and Indu S Ambudkar
J Biol Chem. 2007 Apr 20;282(16):12176-85. [STIM1]

The 1p-encoded protein stathmin and resistance of malignant gliomas to nitrosoureas. TT Ngo, T Peng, XJ Liang, O Akeju, S Pastorino, W Zhang, Y Kotliarov, JC Zenklusen, HA Fine, D Maric, PY Wen, U De Girolami, PM Black, WW Wu, RF Shen, NO Jeffries, DW Kang, and JK Park J Natl Cancer Inst. 2007 Apr 18;99(8):639-52. [STMN1, ENO1, PARK7]

Binding of inhibitory fatty acids is responsible for the enhancement of UDP-glucuronosyltransferase 2B7 (UGT2B7) activity by albumin: Implications for in vitro - in vivo extrapolation. Andrew Rowland, Paraskevi Gaganis, David J Elliot, Peter I Mackenzie, Kathleen M Knights, and John O Miners J Pharmacol Exp Ther. 2007 Apr;321(1):137-47.  [ALB]

Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions. JM Elkins, E Papagrigoriou, G Berridge, X Yang, C Phillips, C Gileadi, P Savitsky, and DA Doyle Protein Sci. 2007 Apr;16(4):683-94. [DLG2, DLG3, MPDZ, SLC9A3R2]

Down-regulation of Apurinic/Apyrimidinic Endonuclease 1/Redox Factor-1 Expression by Soy Isoflavones Enhances Prostate Cancer Radiotherapy In vitro and In vivo. JJ Raffoul, S Banerjee, V Singh-Gupta, ZE Knoll, A Fite, H Zhang, J Abrams, FH Sarkar, and GG Hillman Cancer Res. 2007 Mar 1;67(5):2141-9. [APEX1]

IGF1/insulin signaling activates androgen signaling through direct interactions of FOXO1 with androgen receptor. Wuqiang Fan, Toshihiko Yanase, Hidetaka Morinaga, Taijiro Okabe, Masatoshi Nomura, Hiroaki Daitoku, Akiyoshi Fukamizu, Shigeaki Kato, Ryoichi Takayanagi, and Hajime Nawata J Biol Chem. 2007 Mar 9;282(10):7329-38.  [PTEN]

The brefeldin A-inhibited guanine nucleotide-exchange protein, BIG2, regulates the constitutive release of TNFR1 exosome-like vesicles.
Aminul Islam, Xiaoyan Shen, Toyoko Hiroi, Joel Moss, Martha Vaughan, and Stewart J Levine
J Biol Chem. 2007 Mar 30;282(13):9591-9.  [ARFGEF2, ARF1, ARF3]

Role of the Store-operated Calcium Entry Proteins, Stim1 and Orai1, in Muscarinic-Cholinergic Receptor Stimulated Calcium Oscillations in Human Embryonic Kidney Cells. Barbara Wedel, Rebecca R Boyles, James W Putney, and Gary S Bird
J Physiol. 2007 Mar 15;579(Pt 3):679-89.  [STIM2]

IFI16 in Human Prostate Cancer. Fatouma Alimirah, Jianming Chen, Francesca J Davis, and Divaker Choubey Mol Cancer Res. 2007 Mar;5(3):251-9. [JAK1]

Orai proteins interact with TRPC channels and confer responsiveness to store depletion. Y Liao, C Erxleben, E Yildirim, J Abramowitz, DL Armstrong, and L Birnbaumer Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4682-7. [TMEM142A, TMEM142B, TMEM142C]

Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development. A Abramsson, S Kurup, M Busse, S Yamada, P Lindblom, E Schallmeiner, D Stenzel, D Sauvaget, J Ledin, M Ringvall, U Landegren, L Kjellen, G Bondjers, JP Li, U Lindahl, D Spillmann, C Betsholtz, and H Gerhardt
Genes Dev. 2007 Feb 1;21(3):316-31.  [PDGFB]

SGCE missense mutations that cause myoclonus-dystonia syndrome impair epsilon-sarcoglycan trafficking to the plasma membrane: modulation by ubiquitination and torsinA, Christopher T. Esapa, Adrian Waite, Matthew Locke, Matthew A. Benson, Michaela Kraus, R.A. Jeffrey McIlhinney, Roy V. Sillitoe, Philip W. Beesley, Derek J. Blake Hum Mol Genet. 2007 Feb 1;16(3):327-42. [SGCA, SGCB, SGCE]

Interleukin-31 and oncostatin-M mediate distinct signaling reactions and response patterns in lung epithelial cells. Souvik Chattopadhyay, Erin Tracy, Ping Liang, Olivier Robledo, Stefan Rose-John, and Heinz Baumann J Biol Chem. 2007 Feb 2;282(5):3014-26. [IL22, IL24]

Constitutive Traffic of Melanocortin-4 Receptor in Neuro2A Cells and Immortalized Hypothalamic Neurons  Sameer Mohammad, Giovanna Baldini, Susana Granell, Paola Narducci, Alberto M. Martelli, Giulia Baldini J Biol Chem. 2007 Feb 16;282(7):4963-74. [MC4R]

Human Xylosyltransferase II Is Involved in the Biosynthesis of the Uniform Tetrasaccharide Linkage Region in Chondroitin Sulfate and Heparan Sulfate Proteoglycans Claudia Ponighaus, Michael Ambrosius, Javier Carrera Casanova, Christian Prante, Joachim Kuhn, Jeffrey D. Esko, Knut Kleesiek, Christian Gotting J Biol Chem. 2007 Feb 23;282(8):5201-6. [XYLT2]

Helix-Loop-Helix Protein p8, a Transcriptional Regulator Required for Cardiomyocyte Hypertrophy and Cardiac Fibroblast Matrix Metalloprotease Induction Sandro Goruppi, Richard D. Patten, Thomas Force, John M. Kyriakis Mol Cell Biol. 2007 Feb;27(3):993-1006. [JUN]

RET/papillary thyroid carcinoma oncogenic signaling through the Rap1 small GTPase.
V De Falco, MD Castellone, G De Vita, AM Cirafici, JM Hershman, C Guerrero, A Fusco, RM Melillo, and M Santoro Cancer Res. 2007 Jan 1;67(1):381-90.  [CRK]

The role of activating protein 1 in the transcriptional regulation of the human FCGR2B promoter mediated by the -343 G to C polymorphism associated with systemic lupus erythematosus. Mikhail Olferiev, Emi Masuda, Shizuko Tanaka, Marissa C Blank, and Luminita Pricop J Biol Chem. 2007 Jan 19;282(3):1738-46.  [YY1]

Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury. Li Zhu, Wolfgang Bergmeier, Jie Wu, Hong Jiang, Timothy J Stalker, Marcin Cieslak, Ran Fan, Laurence Boumsell, Atsushi Kumanogoh, Hitoshi Kikutani, Luca Tamagnone, Denisa D Wagner, Marcos E Milla, and Lawrence F Brass
Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1621-6.  [SEMA4D]

CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin
Dominik J. Schaer, Christian A. Schaer, Paul W. Buehler, Robert A. Boykins, Gabriele Schoedon, Abdu I. Alayash, and Andreas Schaffner Blood. 2006 Jan 1;107(1):373-80. [CD163]

Identification of Novel Protein Targets for Modification by 15-Deoxy-delta-12,14-Prostaglandin J2 in Mesangial Cells Reveals Multiple Interactions with the Cytoskeleton Konstantinos Stamatakis, Francisco J. Sánchez-Gómez, and Dolores Pérez-Sala
J. Am. Soc. Nephrol. 2006 Jan;17(1):89-98. [vimentin]

PDSM, a motif for phosphorylation-dependent SUMO modification
Ville Hietakangas, Julius Anckar, Henri A. Blomster, Mitsuaki Fujimoto, Jorma J. Palvimo, Akira Nakai, and Lea Sistonen
Proc Natl Acad Sci U S A. 2006 Jan 3;103(1):45-50.[GATA-1, MEF2A]

The kinase insert domain-containing receptor is an angiogenesis-associated antigen recognized by human cytotoxic T lymphocytes
Yuansheng Sun, Stefan Stevanovic, Mingxia Song, Astrid Schwantes, C. James Kirkpatrick, Dirk Schadendorf, and Klaus Cichutek Blood. 2006 Feb 15;107(4):1476-83. [KDR]

Src Uses Cas to Suppress Fhl1 in Order to Promote Nonanchored Growth and Migration of Tumor Cells Yongquan Shen, Zhenyu Jia, Robert G. Nagele, Hitoshi Ichikawa, and Gary S. Goldberg Cancer Res. 2006 Feb 1;66(3):1543-52. [FHL1]

The CLN9 Protein, a Regulator of Dihydroceramide Synthase
Angela Schulz, Talal Mousallem, Maya Venkataramani, Dixie-Ann Persaud-Sawin, Adam Zucker, Chiara Luberto, Alicja Bielawska, Jacek Bielawski, Joost C. M. Holthuis, S. Michal Jazwinski, Lina Kozhaya, Ghassan S. Dbaibo, and Rose-Mary N. Boustany J. Biol. Chem 2006 Feb 3;281(5):2784-94. [LASS2trv3]

Cardiac-specific overexpression of sarcolipin in phospholamban null mice impairs myocyte function that is restored by phosphorylation
Anthony O. Gramolini, Maria G. Trivieri, Gavin Y. Oudit, Thomas Kislinger, Wenping Li, Mikin M. Patel, Andrew Emili, Evangelia G. Kranias, Peter H. Backx, and David H. MacLennan
Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2446-51. [STK16]

Neuronal Chemorepellent Slit2 Inhibits Vascular Smooth Muscle Cell Migration by Suppressing Small GTPase Rac1 Activation
Dong Liu, Jie Hou, Xing Hu, Xuerong Wang, Yan Xiao, Yongshan Mou, and Hector De Leon
Circ. Res. 2006 Mar 3;98(4):480-9.[Slit-2]

Tuftsin Binds Neuropilin-1 through a Sequence Similar to That Encoded by Exon 8 of Vascular Endothelial Growth Factor
Mathew A. von Wronski, Natarajan Raju, Radhakrishna Pillai, Nancy J. Bogdan, Edmund R. Marinelli, Palaniappa Nanjappan, Kondareddiar Ramalingam, Thangavel Arunachalam, Steve Eaton, Karen E. Linder, Feng Yan, Sibylle Pochon, Michael F. Tweedle, and Adrian D. Nunn J. Biol. Chem. 2006 Mar 3;281(9):5702-10.[NP-1]

IKK alpha Regulates Estrogen-induced Cell Cycle Progression by Modulating E2F1 Expression Zheng Tu, Shashi Prajapati, Kyu-Jin Park, Nathan J. Kelly, Yumi Yamamoto, and Richard B. Gaynor J. Biol. Chem. 2006 Mar 10;281(10):6699-706. [E2F1 and PCAF]

Selective Inhibition of Fibroblast Activation Protein Protease Based on Dipeptide Substrate Specificity Conrad Yap Edosada, Clifford Quan, Christian Wiesmann, Thuy Tran, Dan Sutherlin, Mark Reynolds, J. Michael Elliott, Helga Raab, Wayne Fairbrother, and Beni B. Wolf
J. Biol. Chem. 2006 Mar 17;281(11):7437-44 [DPP-7, DPP-8, DPP-9, prolyl oligopeptidase, and acylpeptide hydrolase]

MyD88 and TNF Receptor-Associated Factor 6 Are Critical Signal Transducers in Helicobacter pylori-Infected Human Epithelial Cells
Yoshihiro Hirata, Tomoya Ohmae, Wataru Shibata, Shin Maeda, Keiji Ogura, Haruhiko Yoshida, Takao Kawabe, and Masao Omata J. Immunol. 2006 Mar 15;176(6):3796-803. [Nod1]

Naloxone acts as an antagonist of estrogen receptor activity in MCF-7 cells
Mariya Farooqui, Zhen H. Geng, Elliot J. Stephenson, Nurulain Zaveri, Douglas Yee, and Kalpna Gupta Mol. Cancer Ther. 2006 Mar;5(3):611-20. [ER alpha]

Targeted Disruption of Fibulin-4 Abolishes Elastogenesis and Causes Perinatal Lethality in Mice
Precious J. McLaughlin, Qiuyun Chen, Masahito Horiguchi, Barry C. Starcher, J. Brett Stanton, Thomas J. Broekelmann, Alan D. Marmorstein, Brian McKay, Robert Mecham, Tomoyuki Nakamura, and Lihua Y. Marmorstein Mol. Cell. Biol. 2006 Mar;26(5):1700-9. [fibulin-4, tropoelastin]

The Saccharomyces cerevisiae Lipin Homolog Is a Mg2+-dependent Phosphatidate Phosphatase Enzyme Gil-Soo Han, Wen-I Wu, and George M. Carman J. Biol. Chem. 2006 Apr 7;281(14):9210-8.[LPIN1]

ATM Activation by Ionizing Radiation Requires BRCA1-associated BAAT1
Jason A. Aglipay, Sarah A. Martin, Hideyuki Tawara, Sam W. Lee, and Toru Ouchi
J. Biol. Chem. 2006 Apr 7;281(14):9710-8. [LPPRP2]

Determinants of specific RNA interference-mediated silencing of human beta-globin alleles differing by a single nucleotide polymorphism Derek M. Dykxhoorn, Lisa D. Schlehuber, Irving M. London, and Judy Lieberman
Proc Natl Acad Sci USA 2006 Apr 11;103(15):5953-8. [beta A and gamma-globin]

 Atherosclerotic Plaque Macrophage Transcriptional Regulators Are Expressed in Blood and Modulated by Tristetraprolin Willmar D. Patino, Ju-Gyeong Kang, Satoaki Matoba, Omar Y. Mian, Bernadette R. Gochuico, and Paul M. Hwang Circ. Res. 2006 May 26;98(10):1282-9.[TTP]

Posttranslational N-Myristoylation Is Required for the Anti-apoptotic Activity of Human Gelsolin, the C-terminal Caspase Cleavage Product of Human Gelsolin
Nagisa Sakurai and Toshihiko Utsumi J. Biol. Chem. 2006 May 19;281(20):14288-95.[gelsolin]

Role of ETS Transcription Factors in the Hypoxia-Inducible Factor-2 Target Gene Selection Olga Aprelikova, Matthew Wood, Sean Tackett, Gadisetti V.R. Chandramouli, and J. Carl BarrettCancer Res. 2006 Jun 1;66(11):5641-7. [ELK-1]

Diagnosis of Suspicious Thyroid Nodules Using Four Protein Biomarkers
Janete M. Cerutti, Flavia R.M. Latini, Claudia Nakabashi, Rosana Delcelo, Victor P. Andrade, Marcelo João Amadei, Rui M.B. Maciel, Flavio C. Hojaij, Donna Hollis, Jennifer Shoemaker, and Gregory J. Riggins Clin. Cancer Res. 2006 Jun 1;12(11 Pt 1):3311-8. [C1orf24, ITM1]

Oxysterol-binding Protein and Vesicle-associated Membrane Protein–associated Protein Are Required for Sterol-dependent Activation of the Ceramide Transport Protein Ryan J. Perry and Neale D. Ridgway Mol. Biol. Cell. 2006 Jun;17(6):2604-16. [CERT]

Molecular Identification and Characterization of a Family of Kinases with Homology to Ca2+/Calmodulin-dependent Protein Kinases I/IV
Shogo Ohmae, Sayaka Takemoto-Kimura, Michiko Okamura, Aki Adachi-Morishima, Mio Nonaka, Toshimitsu Fuse, Satoshi Kida, Masahiro Tanji, Tomoyuki Furuyashiki, Yoshiki Arakawa, Shuh Narumiya, Hiroyuki Okuno, and Haruhiko Bito J. Biol. Chem., Jul 2006; 281: 20427-20439.[Torc2]

Orai1 and STIM Reconstitute Store-operated Calcium Channel Function
Jonathan Soboloff, Maria A. Spassova, Xiang D. Tang, Thamara Hewavitharana, Wen Xu, and Donald L. Gill J. Biol. Chem., Jul 2006; 281: 20661-20665.[Orai1]

Ca2+/Calmodulin-Dependent Protein Kinase II Is a Modulator of CARMA1-Mediated NF-kappa B Activation
Kazuhiro Ishiguro, Todd Green, Joseph Rapley, Heather Wachtel, Cosmas Giallourakis, Aimee Landry, Zhifang Cao, Naifang Lu, Ando Takafumi, Hidemi Goto, Mark J. Daly, and Ramnik J. Xavier
Mol. Cell. Biol., Jul 2006; 26:5497-5508.[CamKII]

The active metabolite of Clopidogrel disrupts P2Y12 receptor oligomers and partitions them out of lipid rafts
Pierre Savi, Jean-Luc Zachayus, Nathalie Delesque-Touchard, Catherine Labouret, Caroline Hervé, Marie-Françoise Uzabiaga, Jean-Marie Pereillo, Jean-Michel Culouscou, Françoise Bono, Pascual Ferrara, and Jean-Marc Herbert PNAS, Jul 2006; 103: 11069 - 11074. [P2Y1, P2Y12, P2Y13]

Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration
Benoit Favier, Antoine Alam, Pauline Barron, Jacques Bonnin, Patricia Laboudie, Pierre Fons, Marie Mandron, Jean-Pascal Herault, Gera Neufeld, Pierre Savi, Jean-Marc Herbert, and Françoise Bono
Blood, Aug 2006; 108: 1243-1250.[Sema3F]

The Aurora Kinase Inhibitor VX-680 Induces Endoreduplication and Apoptosis Preferentially in Cells with Compromised p53-Dependent Postmitotic Checkpoint Function Farid Gizatullin, Yao Yao, Victor Kung, Matthew W. Harding, Massimo Loda, and Geoffrey I. Shapiro Cancer Res., Aug 2006; 66: 7668 - 7677. [p21waf1cip1]

Regulation of Nucleocytoplasmic Trafficking of Transcription Factor OREBP/TonEBP/NFAT5 Edith H. Y. Tong, Jin-Jun Guo, Ai-Long Huang, Han Liu, Chang-Deng Hu, Stephen S. M. Chung, and Ben C. B. Ko J. Biol. Chem., 2006 Aug 18;281(33):23870-9. [CMR1]

Large Store-operated Calcium Selective Currents Due to Co-expression of Orai1 or Orai2 with the Intracellular Calcium Sensor, Stim1 Jason C. Mercer, Wayne I. DeHaven, Jeremy T. Smyth, Barbara Wedel, Rebecca R. Boyles, Gary S. Bird, and James W. Putney, Jr J. Biol. Chem., 2006 Aug 25;281(34):24979-90.[Stim1, Orai1, Orai2, Orai3]

Selective modulation of protein kinase A I and II reveals distinct roles in thyroid cell gene expression and growth. Davide Calebiro, Tiziana de Filippis, Simona Lucchi, Fernando Martinez, Patrizia Porazzi, Roberta Trivellato, Massimo Locati, Paolo Beck-Peccoz and Luca Persani Mol Endocrinol. 2006 Dec;20(12):3196-211. [Prkar2b]

Ligand-Independent Homo- and Heterodimerization of Human Prolactin Receptor Variants: Inhibitory Action of the Short Forms by Heterodimerization
Aamer M. Qazi, Chon-Hwa Tsai-Morris, and Maria L. Dufau
Mol. Endocrinol., Aug 2006; 20: 1912 - 1923. [JAK2]

Evidence of a Potential Receptor-Binding Site on the Nipah Virus G Protein (NiV-G): Identification of Globular Head Residues with a Role in Fusion Promotion and Their Localization on an NiV-G Structural Model
Vanessa Guillaume, Hamide Aslan, Michelle Ainouze, Mathilde Guerbois, T. Fabian Wild, Robin Buckland, and Johannes P. M. Langedijk J. Virol., Aug 2006; 80: 7546 - 7554.[ephrin B2]

The Expression of CD30 in Anaplastic Large Cell Lymphoma Is Regulated by Nucleophosmin-Anaplastic Lymphoma Kinase–Mediated JunB Level in a Cell Type–Specific Manner Faye Yuan-Yi Hsu, Patrick B. Johnston, Kathleen A. Burke, and Yi Zhao
Cancer Res. 2006 Sep 15;66(18):9002-8. [JunB]

Allelic mRNA expression of X-linked monoamine oxidase a (MAOA) in human brain: dissection of epigenetic and genetic factors Julia K. Pinsonneault, Audrey C. Papp, and Wolfgang Sadée Hum. Mol. Genet., Sep 2006; 15: 2636-2649. [MAOA]

C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1 Chou Hung Sim, Daisy Sio Seng Lio, Su San Mok, Colin L. Masters, Andrew F. Hill, Janetta G. Culvenor and Heung-Chin Cheng Hum Mol Genet. 2006 Nov 1;15(21):3251-62.[PINK1]

Human Mitochondrial DNA Nucleoids Are Linked to Protein Folding Machinery and Metabolic Enzymes at the Mitochondrial Inner Membrane
Yousong Wang and Daniel F. Bogenhagen J. Biol. Chem., 2006 Sep 1;281(35):25791-802.[DHX30]

Inhibition of gluconeogenesis through transcriptional activation of EGR1 and DUSP4 by AMPK Stephen P. Berasi, Christine Huard, Dongmei Li, Heather H. Shih, Ying Sun, Wenyan Zhong, Janet E. Paulsen, Eugene L. Brown, Ruth E. Gimeno, and Robert V. Martinez
J. Biol. Chem. 2006 Sep 15;281(37):27167-77.[DUSP4]

Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane
Minnie M. Wu, JoAnn Buchanan, Riina M. Luik, and Richard S. Lewis
J. Cell Biol. 2006 Sep 11;174(6):803-13.  [Stim1]

The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER–plasma membrane junctions
Riina M. Luik, Minnie M. Wu, JoAnn Buchanan, and Richard S. Lewis
J. Cell Biol. 2006 Sep 11;174(6):815-25. [Stim1]

Dysfusion Transcriptional Control of Drosophila Tracheal Migration, Adhesion, and Fusion Lan Jiang and Stephen T. Crews Mol. Cell. Biol. Sep 2006; 26: 6547 - 6556.[apt, btl, cdi, CG13196, CG15252, esg, hdc, kni, knrl, trh, vvl]

Phosphatidylinositol 3-Kinase/Protein Kinase C -Induced Phosphorylation of Sp1 and p107 Repressor Release Have a Critical Role in Histone Deacetylase Inhibitor-Mediated Depression of Transcription of the Luteinizing Hormone Receptor Gene Ying Zhang, Mingjuan Liao, and Maria L. Dufau Mol. Cell. Biol., Sep 2006; 26: 6748 - 6761. [Sp1, pRb, p107]

Different abilities of the four FGFRs to mediate FGF-1 translocation are linked to differences in the receptor C-terminal tail
Vigdis Sørensen, Antoni Wiedlocha, Ellen Margrethe Haugsten, Denis Khnykin, Jørgen Wesche, and Sjur Olsnes J. Cell Sci. 2006 Oct 15;119(Pt 20):4332-41. [FGFR2]

Dosage-Sensitive Sex Reversal Adrenal Hypoplasia Congenita Critical Region on the X Chromosome, Gene 1 (DAX1) (NR0B1) and Small Heterodimer Partner (SHP) (NR0B2) Form Homodimers Individually, as Well as DAX1-SHP Heterodimers Anita K. Iyer, Yao-Hua Zhang, and Edward R. B. McCabe Mol. Endocrinol. 2006 Oct;20(10):2326-42. [SHP, ERalpha]

A retrovirus-based protein complementation assay screen reveals functional AKT1-binding partners. Zhiyong Ding, Jiyong Liang, Yiling Lu, Qinghua Yu, Zhou Songyang, Shiaw-Yih Lin, and Gordon B Mills Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15014-9. [ACTN4]

A missense mutation in Caenorhabditis elegans prohibitin 2 confers an atypical multidrug resistance. Iryna Zubovych, Thomas Doundoulakis, Patrick G Harran, and Michael G Roth Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15523-8. [PHB2]

Regulation of the human biotin transporter hSMVT promoter by KLF-4 and AP-2: confirmation of promoter activity in vivo. Jack C Reidling and Hamid M Said Am J Physiol Cell Physiol. 2006 Nov 29; [KLF4]

C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1
Chou Hung Sim, Daisy Sio Seng Lio, Su San Mok, Colin L. Masters, Andrew F. Hill, Janetta G. Culvenor, and Heung-Chin Cheng Hum. Mol. Genet. 2006 Nov 1;15(21):3251-62. [PINK1]

Effects on ligand interaction and membrane translocation of the positively charged arginine residues situated along the C1 domain binding cleft in the atypical protein kinase C isoforms Yongmei Pu, Megan L. Peach, Susan H. Garfield, Stephen Wincovitch, Victor E. Marquez, and Peter M. Blumberg J. Biol. Chem., 2006 Nov 3;281(44):33773-88. [PKC isoforms]

Necessary Role for the Lag1p Motif in (Dihydro)ceramide Synthase Activity Stefka Spassieva, Jae-Gu Seo, James C. Jiang, Jacek Bielawski, Fernando Alvarez-Vasquez, S. Michal Jazwinski, Yusuf A. Hannun, and Lina M. Obeid J Biol Chem. 2006 Nov 10;281(45):33931-8.[Lass5]

Cisplatin and oxaliplatin, but not carboplatin and nedaplatin, are substrates for human organic cation transporters (SLC22A1-3 and MATE family) Atsushi Yonezawa, Satohiro Masuda, Sachiko Yokoo, Toshiya Katsura, and Ken-ichi Inui
J. Pharmacol. Exp. Ther., 2006 Nov;319(2):879-86.

Human xylosyltransferase II is involved in the biosynthesis of the uniform tetrasaccharide linkage region in chondroitin sulphate and heparan sulphate proteoglycans. Claudia Ponighaus, Michael Ambrosius, Javier Carrera Casanova, Christian Prante, Joachim Kuhn, Jeffrey D Esko, Knut Kleesiek, and Christian Gotting
J Biol Chem. 2006 Dec 22; [Epub ahead of print] [XYLT2]

Selective modulation of PKA I and II reveals distinct roles in thyroid cell gene expression and growth Davide Calebiro, Tiziana de Filippis, Simona Lucchi, Fernando Martinez, Patrizia Porazzi, Roberta Trivellato, Massimo Locati, Paolo Beck-Peccoz, and Luca Persani
Mol. Endocrinol., 2006 Dec;20(12):3196-211.[Pkar2b]


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