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IAPP IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo, Venkatanarayan, A;Raulji, P;Norton, W;Chakravarti, D;Coarfa, C;Su, X;Sandur, SK;Ramirez, MS;Lee, J;Kingsley, CV;Sananikone, EF;Rajapakshe, K;Naff, K;Parker-Thornburg, J;Bankson, JA;Tsai, KY;Gunaratne, PH;Flores, ER;, Nature Nov 2014 RC215074

IARS2 Isoleucyl-tRNA synthetase levels modulate the penetrance of a homoplasmic m.4277T>C mitochondrial tRNAIle mutation causing hypertrophic cardiomyopathy, Elena Perli, Carla Giordano, Helen A.L. Tuppen, Monica Montopoli, Arianna Montanari, Maurizia Orlandi, Annalinda Pisano, Daniela Catanzaro, Laura Caparrotta, Beatrice Musumeci, Camillo Autore, Veronica Morea, Patrizio Di Micco, Antonio F. Campese, Martina Leopizzi, Pietro Gallo, Silvia Francisci, Laura Frontali, Robert W. Taylor, and Giulia d'Amati, Hum. Mol. Genet., Jan 2012; 21: 85 - 100. RC211919

IARS2 Isoleucyl-tRNA synthetase levels modulate the penetrance of a homoplasmic m.4277T>C mitochondrial tRNAIle mutation causing hypertrophic cardiomyopathy, Elena Perli, Carla Giordano, Helen A.L. Tuppen, Monica Montopoli, Arianna Montanari, Maurizia Orlandi, Annalinda Pisano, Daniela Catanzaro, Laura Caparrotta, Beatrice Musumeci, Camillo Autore, Veronica Morea, Patrizio Di Micco, Antonio F. Campese, Martina Leopizzi, Pietro Gallo, Silvia Francisci, Laura Frontali, Robert W. Taylor, and Giulia d'Amati, Hum. Mol. Genet., Oct 2011; 10.1093/hmg/ddr440. RC211919

IASPP Suppression of iASPP-dependent aggressiveness in cervical cancer through reversal of methylation silencing of microRNA-124, Dong, P;Xiong, Y;Watari, H;Hanley, SJ;Konno, Y;Ihira, K;Suzuki, F;Yamada, T;Kudo, M;Yue, J;Sakuragi, N;, Sci Rep 2016 RC207150

IBA57 Mutation of the iron-sulfur cluster assembly gene IBA57 causes severe myopathy and encephalopathy, Nikhita Ajit Bolar, Arnaud Vincent Vanlander, Claudia Wilbrecht, Nathalie Van der Aa, Joél Smet, Boel De Paepe, Geert Vandeweyer, Frank Kooy, François Eyskens, Elien De Latter, Gwenda Delanghe, Paul Govaert, Jules Gerard Leroy, Bart Loeys, Roland Lill, Lut Van Laer, and Rudy Van Coster, Hum. Mol. Genet., Jul 2013; 22: 2590 - 2602. RC211947

IBTK CRL3IBTK Regulates the Tumor Suppressor Pdcd4 through Ubiquitylation Coupled to Proteasomal Degradation, Pisano, A;Ceglia, S;Palmieri, C;Vecchio, E;Fiume, G;De Laurentiis, A;Mimmi, S;Falcone, C;Iaccino, E;Scialdone, A;Pontoriero, M;Fasanella Masci, F;Valea, R;Krishnan, S;Gaspari, M;Cuda, G;Scala, G;Quinto, I;, J. Biol. Chem. Apr 2015 RC218657

ICAM1 Release of VSVG-pseudotyped Lentivirus from the Host Cell is impaired upon Low-density Lipoprotein Receptor Overexpression, Otahal, A;Fuchs, R;Al-Allaf, FA;Blaas, D;, J. Virol. Sep 2015 RC200714

ICAM1 The dendritic cell cytoskeleton promotes T cell adhesion and activation by constraining ICAM-1 mobility, Comrie, WA;Li, S;Boyle, S;Burkhardt, JK;, J. Cell Biol. Feb 2015 MR227081

ICK An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome., Paige Taylor, S;Kunova Bosakova, M;Varecha, M;Balek, L;Barta, T;Trantirek, L;Jelinkova, I;Duran, I;Vesela, I;Forlenza, KN;Martin, JH;Hampl, A;, ;Bamshad, M;Nickerson, D;Jaworski, ML;Song, J;Wan Ko, H;Cohn, DH;Krakow, D;Krejci, P;, Hum. Mol. Genet. 2016 RC213609

ICK An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signaling and causes short rib polydactyly syndrome , Taylor, SP;Bosakova, MK;Varecha, M;Balek, L;Barta, T;Trantirek, L;Jelinkova, I;Duran, I;Vesela, I;Forlenza, KN;Martin, JH;Hampl, A;Genomics, Uo;Bamshad, M;Nickerson, D;Jaworski, ML;Song, J;Ko, HW;Cohn, DH;Krakow, D;Krejci, P;, Human Molecular Genetics 2016 RC213609

ICK Understanding the function and mechanisms of intestinal cell kinase in the growth and survival of prostate cancer cells, Wilce, AJ;, Thesis Aug 2015 RG216454

ICOSLG ICOSL expression in human bone marrow-derived mesenchymal stem cells promotes induction of regulatory T cells, Lee, HJ;Kim, SN;Jeon, MS;Yi, T;Song, SU;, Sci Rep 2017 RG208975

ID4 miRNA-342 regulates CEACAM1-induced lumen formation in a 3D model of mammary gland morphogenesis , Weng, C;Nguyen, T;Shively, JE;, Journal of Biological Chemistry 2016 RC204170

IDE Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease, Son, SM;Cha, MY;Choi, H;Kang, S;Choi, H;Lee, MS;Park, SA;Mook-Jung, I;, Autophagy Mar 2016 RG220700

IDH1 Targeted rescue of cancer-associated IDH1 mutant activity using an engineered synthetic antibody, Rizk, SS;Mukherjee, S;Koide, A;Koide, S;Kossiakoff, AA;, Sci Rep 2017 RC210582

IDH1 Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation, Richarson, AD;Scott, DA;Zagnitko, O;Aza-Blanc, P;Chang, CC;Russler-Germain, DA;Reproducibility Project: Cancer Biology, ;, Elife Mar 2016 RC210582

IDH1 Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation, Richarson, AD;Scott, DA;Zagnitko, O;Aza-Blanc, P;Chang, CC;Russler-Germain, DA;Reproducibility Project: Cancer Biology, ;, Elife Mar 2016 RC400096

IDH1 Metabolomic comparison between cells overexpressing isocitrate dehydrogenase 1 and 2 mutants and the effects of an inhibitor on the metabolism, Wen, H;Cho, HR;Yun, T;Kim, H;Park, CK;Lee, SH;Choi, SH;Park, S;, J. Neurochem. Sep 2014 RC210582

IDH2 Replication Study: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate, Showalter, MR;Hatakeyama, J;Cajka, T;VanderVorst, K;Carraway, KL;Fiehn, O;, ;, Elife 2017 RC201152

IDH2 Replication Study: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate, Showalter, MR;Hatakeyama, J;Cajka, T;VanderVorst, K;Carraway, KL;Fiehn, O;, ;, Elife 2017 RC400103

 

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