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shRNA Citations

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MAD2L1 Phosphoinositide 3-kinase ß regulates chromosome segregation in mitosis, Virginia Silió, Javier Redondo-Muñoz, and Ana C. Carrera, Mol. Biol. Cell, Dec 2012; 23: 4526 - 4542. TG311623

MAFA Calcineurin/Nuclear Factor of Activated T Cells and MAPK Signaling Induce TNF-{alpha} Gene Expression in Pancreatic Islet Endocrine Cells, Michael C. Lawrence, Bashoo Naziruddin, Marlon F. Levy, Andrew Jackson, and Kathleen McGlynn, J. Biol. Chem., Jan 2011; 286: 1025 - 1036 TR303385

MAGMAS Magmas, a Gene Newly Identified as Overexpressed in Human and Mouse ACTH-Secreting Pituitary Adenomas, Protects Pituitary Cells from Apoptotic Stimuli, Federico Tagliati, Erica Gentilin, Mattia Buratto, Daniela Molè, Ettore Ciro degli Uberti, and Maria Chiara Zatelli, Endocrinology, Oct 2010; 151: 4635 - 4642 TR513987

MAP1LC3B Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways, Huang, WR;Chiu, HC;Liao, TL;Chuang, KP;Shih, WL;Liu, HJ;, PLoS ONE Aug 2015 TG503902

MAP2K1 Cyclin-dependent kinase 5 contributes to endoplasmic reticulum stress induced podocyte apoptosis via promoting MEKK1 phosphorylation at Ser280 in diabetic nephropathy, Zhang, Y;Gao, X;Chen, S;Zhao, M;Chen, J;Liu, R;Cheng, S;Qi, M;Wang, S;Liu, W;, Cell. Signal 2016 TR502589

MAP2K3 The survival kinase Mirk/dyrk1B is activated through Rac1-MKK3 signaling, Jin K, Lim S, Mercer SE, Friedman E., J Biol Chem. 2005 Dec 23;280(51):42097-105. TR320491

MAP3K8 Tpl2 Is a Key Mediator of Arsenite-Induced Signal Transduction, Kyung Mi Lee, Ki Won Lee, Ann M. Bode, Hyong Joo Lee, and Zigang Dong, Cancer Res., Oct 2009; 69: 8043 - 8049 TR512220

MAPK8 Plumbagin induces apoptosis in lymphoma cells via oxidative stress mediated glutathionylation and inhibition of mitogen-activated protein kinase phosphatases (MKP1/2), Checker, R;Gambhir, L;Sharma, D;Kumar, M;Sandur, SK;, Cancer Lett. Nov 2014 TR511480

MAPKAPK2 Phosphorylation of the RNA-binding protein Dazl by MAPKAP kinase 2 regulates spermatogenesis, Williams, PA;Krug, MS;McMillan, EA;Peake, JD;Davis, TL;Cocklin, S;Strochlic, TI;, Mol. Biol. Cell 2016 TR320609

MAPKAPK2 Phosphorylation of the RNA-binding protein Dazl by MAPKAP kinase 2 regulates spermatogenesis, Williams, PA;Krug, MS;McMillan, EA;Peake, JD;Davis, TL;Cocklin, S;Strochlic, TI;, Mol. Biol. Cell 2016 TR320609

MAPT Glucocorticoids activate a synapse weakening pathway culminating in tau phosphorylation in the hippocampus, Yi, JH;Brown, C;Whitehead, G;Piers, T;Lee, YS;Perez, CM;Regan, P;Whitcomb, DJ;Cho, K;, Pharmacol. Res. 2017 TG710015

MAPT Tau Phosphorylation at Serine 396 Residue Is Required for Hippocampal LTD, Regan, P;Piers, T;Yi, JH;Kim, DH;Huh, S;Park, SJ;Ryu, JH;Whitcomb, DJ;Cho, K;, J. Neurosci. Mar 2015 TG710015

MARK4 MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism, Li, X;Thome, S;Ma, X;Amrute-Nayak, M;Finigan, A;Kitt, L;Masters, L;James, JR;Shi, Y;Meng, G;Mallat, Z;, Nat Commun 2017 TL303343

MCAM CD146 is a novel marker for highly tumorigenic cells and a potential therapeutic target in malignant rhabdoid tumor, Nodomi, S;Umeda, K;Saida, S;Kinehara, T;Hamabata, T;Daifu, T;Kato, I;Hiramatsu, H;Watanabe, KI;Kuwahara, Y;Iehara, T;Adachi, S;Konishi, E;Nakahata, T;Hosoi, H;Heike, T;, Oncogene Apr 2016 TG311550

MCL1 ER Stress-Mediated Upregulation of miR-29a Enhances Sensitivity to Neuronal Apoptosis, Nolan, K;Walter, F;Tuffy, LP;Poeschel, S;Gallagher, R;Haunsberger, S;Bray, I;Stallings, RL;Concannon, CG;Prehn, JH;, Eur. J. Neurosci. Jan 2016 TG303313

MCL1 Dinaciclib, a CDK inhibitor promotes proteasomal degradation of Mcl-1 and enhances ABT-737 mediated cell death in malignant human glioma cell lines, Jane, EP;Premkumar, DR;Cavaleri, JM;Sutera, PA;Rajasekar, T;Pollack, I;, J. Pharmacol. Exp. Ther. Nov 2015 TR303313

MCL1 Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis, Murphy, AC;Weyhenmeyer, B;Noonan, J;Kilbride, SM;Schimansky, S;Loh, KP;Kögel, D;Letai, AG;Prehn, JH;Murphy, BM;, Apoptosis Nov 2013 TG303313

MCL1 Survivin Inhibitor YM-155 Sensitizes Tumor Necrosis Factor– Related Apoptosis-Inducing Ligand-Resistant Glioma Cells to Apoptosis through Mcl-1 Downregulation and by Engaging the Mitochondrial Death Pathway, Daniel R. Premkumar, Esther P. Jane, Kimberly A. Foster, and Ian F. Pollack, J. Pharmacol. Exp. Ther., Aug 2013; 346: 201 - 210. TG303313

MCL1 YM-155 Potentiates the Effect of ABT-737 in Malignant Human Glioma Cells via Survivin and Mcl-1 Downregulation in an EGFR-Dependent Context, Esther P. Jane, Daniel R. Premkumar, Joseph D. DiDomenico, Bo Hu, Shi-Yuan Cheng, and Ian F. Pollack, Mol. Cancer Ther., Mar 2013; 12: 326 - 338. TG303313

MCL1 Inhibition of NF-{kappa}B Signaling by Quinacrine Is Cytotoxic to Human Colon Carcinoma Cell Lines and Is Synergistic in Combination with Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) or Oxaliplatin, Tanvi S. Jani, Jennifer DeVecchio, Tapati Mazumdar, Akwasi Agyeman, and Janet A. Houghton, J. Biol. Chem., Jun 2010; 285: 19162 - 19172 TR303313

 

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