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Home siRNA SR304625

STAT5B (ID 6777) Trilencer-27 Human siRNA

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Specifications Citations Related Products Product Documents
Catalog No. Description Price Availability*  
SR304625
  • STAT5B (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 6777)
  • Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
300
$200
In Stock Add to Shopping Cart
TT300001
  • SiTran1.0: Transfection reagent designed for RNAi duplex (0.5 ml)
$220 In Stock Add to Shopping Cart
* These siRNA duplexes were designed to be effective against all transcriptional variants at this gene locus.
** Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping.
*** Promotion ends Sept 30th.
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Also for STAT5B (Locus ID 6777)
cDNA Clone qPCR Master Mix Primer Pair shRNA Antibody
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OriGene Data
Amount: 2 nmol each, lyophilizedPurity: HPLC purified
Quality Control: Tested by ESI-MSSequences: Available with shipment
Stability: One year from date of shipment when stored at -20ºCShipment: Ambient
# of transfections: Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM)
Note: Single siRNA duplex (10nmol) can be ordered. See details at http://www.origene.com/siRNA/

Reference Data
RefSeq: NM_012448
Synonyms: STAT5
Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008].
Performance Guranteed:
OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency.

For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).

 

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