Mitogen-Activated Protein Kinase-Dependent Interleukin-1a Intracrine Signaling Is Modulated by YopP during Yersinia enterocolitica Infection
Infect. Immun., Jan 2012; 80: 289 - 297.
[IL1A]
ETS1 transcriptional activity is increased in advanced prostate cancer and promotes the castrate-resistant phenotype
Carcinogenesis, Jan 2012; 10.1093/carcin/bgs007.
[ETS1
]
PNAS Plus: TANK-binding kinase 1 (TBK1) controls cell survival through PAI-2/serpinB2 and transglutaminase 2
PNAS, Jan 2012; 109: E177 - E186.
[SERPINB2
]
Heparanase and Syndecan-1 Interplay Orchestrates Fibroblast Growth Factor-2-induced Epithelial-Mesenchymal Transition in Renal Tubular Cells
J. Biol. Chem., Jan 2012; 287: 1478 - 1488.
[HPSE
]
RBFOX1 (Locus ID 54715) Trilencer-27 Human siRNA
Specifications
Related Products
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Catalog No.
Description
Price
Shipping
SR310201
A2BP1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID = 54715)
$ 390
Next Day
SR30004
Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
Included for free
SR30005
RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Included for free
Click here to purchase positive control and fluorescent transfection control.
* These siRNA duplexes were designed to be effective against all transcriptional variants at this gene locus.
Summary: Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined. [provided by RefSeq].
Performance Guranteed:
OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency.
For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).
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