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OriGene shRNA in recent publications
Mitogen-Activated Protein Kinase-Dependent Interleukin-1a Intracrine Signaling Is Modulated by YopP during Yersinia enterocolitica Infection Infect. Immun., Jan 2012; 80: 289 - 297. [IL1A]

ETS1 transcriptional activity is increased in advanced prostate cancer and promotes the castrate-resistant phenotype Carcinogenesis, Jan 2012; 10.1093/carcin/bgs007. [ETS1 ]

PNAS Plus: TANK-binding kinase 1 (TBK1) controls cell survival through PAI-2/serpinB2 and transglutaminase 2 PNAS, Jan 2012; 109: E177 - E186. [SERPINB2 ]

Heparanase and Syndecan-1 Interplay Orchestrates Fibroblast Growth Factor-2-induced Epithelial-Mesenchymal Transition in Renal Tubular Cells J. Biol. Chem., Jan 2012; 287: 1478 - 1488. [HPSE ]

ADRB1 (Locus ID 153) Trilencer-27 Human siRNA

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Specifications Related Products Product Manual FAQs
Catalog No. Description Price Shipping
SR300106 ADRB1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID = 153) $ 390 2 weeks
SR30004 Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included for free
SR30005 RNAse free siRNA Duplex Resuspension Buffer - 2 ml Included for free
Click here to purchase positive control and fluorescent transfection control. Add to Shopping Cart
* These siRNA duplexes were designed to be effective against all transcriptional variants at this gene locus.

Also for ADRB1 (NM_000684)
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OriGene Data
Amount:2 nmol each, lyophilizedPurity:HPLC purified
Quality Control:Tested by ESI-MSSequences:Available with shipment
Stability:One year from date of shipment when stored at -20ºCShipment: Ambient
# of transfections:Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM)

Reference Data
RefSeq: NM_000684
Synonyms: ADRB1R; B1AR; BETA1AR; RHR
Summary: The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq].
Performance Guranteed:
OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency.

For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).

 

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