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OriGene shRNA in recent publications
Identification of CTCF as a master regulator of the clustered protocadherin genes Nucleic Acids Res., Apr 2012; 40: 3378 - 3391. [CTCF ]
Transducin-like Enhancer of Split-1 (TLE1) Combines with Forkhead Box Protein G1 (FoxG1) to Promote Neuronal Survival J. Biol. Chem., Apr 2012; 287: 14749 - 14759. [Tle1 ]
Motoneurons Secrete Angiogenin to Induce RNA Cleavage in Astroglia J. Neurosci., Apr 2012; 32: 5024 - 5038. [GFP-tagged siRNA]
CCR7/CCL19 Controls Expression of EDG-1 in T Cells J. Biol. Chem., Apr 2012; 287: 11656 - 11664. [CCL19 ]

Trilencer-27 - Guaranteed knockdown for siRNA gene silencing

Genomewide coverage against human, mouse and rat
27mer siRNA

Trilencer-27 siRNA kit contains Dicer-Substrate duplexes that provide two critical improvements over the use of traditional 21mer siRNA designs.

27 mer siRNA takes advantage of the natural processing by Dicer producing 10-fold higher potency and specificity than shorter 21mer RNAi forms.

27 mer dicer-substrate duplexes also evade the radar of the mammalian interferon response when expressed in mammalian cells and initiates strong and specific gene silencing.

By its optimal design, Trilencer-27 siRNA has the advantages of improved efficacy and minimal interferon response.

Dicer-Substrate Technology in Nature Publication

Features & Benefits:

  • Genomewide coverage against human, mouse and rat
  • 27mer Dicer-substrate duplex--higher potency & minimal interferon response
  • Guaranteed gene knockdown (≥70%)
  • 3 gene-specific siRNAs + 1 negative control
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SKU Description Price Shipping
SR3XXXXX Gene-specific 3 unique 27mer siRNA duplexes - 2 nmol each + 1 negative control - 2 nmol $390 Varies
SRXXXXXXa/b/c Single siRNA duplex (10nmol), no scrambled control included $300 1 week

Related Products

SKU Description Price Delivery Data Sheet  
SR30002 Trilencer-27 Fluorescent-labeled transfection control siRNA duplex - 1 nmol $100 Immediate Add to Shopping Cart
SR30003 Trilencer-27 HPRT Positive control siRNA duplex - 1 nmol $100 Immediate Add to Shopping Cart
SR30004 Trilencer-27 Universal scrambled negative control siRNA duplex - 2 nmol $100 Immediate Add to Shopping Cart
TT300001 SiTran1.0: Transfection reagent designed for RNAi duplex (0.5 ml) $210 Next day   Add to Shopping Cart

siTran siRNA transfection reagent is designed to achieve high efficiency transfection for siRNA and plasmid DNA. It has been successfully used in T-cell transfection. Learn more about siTran

Useful Links

Manual Application FAQ

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