Trilencer-27 - Guaranteed knockdown for siRNA gene silencing

Genomewide coverage against human

Trilencer-27 siRNA kit contains Dicer-Substrate duplexes that provide two critical improvements over the use of traditional 21mer siRNA designs.

27 mer siRNA takes advantage of the natural processing by Dicer producing 10-fold higher potency and specificity than shorter 21mer RNAi forms.

27 mer dicer-substrate duplexes also evade the radar of the mammalian interferon response when expressed in mammalian cells and initiates strong and specific gene silencing.

By its optimal design, Trilencer-27 siRNA has the advantages of improved efficacy and minimal interferon response.

Dicer-Substrate Technology in Nature Publication

Features & Benefits:

• Genomewide coverage against human
• 27mer Dicer-substrate duplex--higher potency & minimal interferon response
• Guaranteed gene knockdown (≥70%)
• 3 gene-specific siRNAs + 1 negative control

SKU Description Price Delivery Data Sheet   SR30002 Trilencer-27 Fluorescent-labeled transfection control siRNA duplex - 1 nmol $100 Immediate SR30003 Trilencer-27 HPRT Positive control siRNA duplex - 1 nmol $100 Immediate SR30004 Trilencer-27 Universal scrambled negative control siRNA duplex - 2 nmol $100 Immediate

siTran siRNA transfection reagent is designed to achieve high efficiency transfection for siRNA and plasmid DNA. It has been successfully used in T-cell transfection. Learn more about siTran

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