OriGene cDNA clones in recent publications
Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease Nat. Genet. Jan 2016
Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma Journal of the Neurological Sciences Jan 2016
The New Role of CD163 in the Differentiation of Bone Marrow Stromal Cells into Vascular Endothelial-Like Cells Stem Cells International Jan 2016
a-Helix-Peptides Composing the Human Nuclear Receptor ERR? Competitively Provoke Inhibition of Functional Homomeric Dimerization Biopolymers Dec 2015
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- The cDNA libraries were designed as to complement the DupLEX-A yeast two-hybrid system. The cDNA are cloned downstream of B42-HA domain under Gal promoter. For the customer who already have the Duplex-A system in house, the libraries can be used for identification of novel protein interactions with a bait protein.
- Once positive clone is identified, the plasmid can be used to express fusion protein with HA tag which allows detection with HA antibody.
- The library can be used as cDNA template to PCR amplify target genes or gene fragments with specific primer pairs.
- The library can be used as standard plasmid libraries for isolation of cDNA clones using conventional nucleic acid-based screening strategies.