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OriGene's Functional Kinome Collection Published in Cell
Rockville, MD. May 2nd, 2008 Scientists from University of Helsinki, Institute of Molecular Medicine in Finland and OriGene Technologies joined effort in creating the most comprehensive kinome collection of nearly all predicted human protein kinases, including the functional kinases and their kinase-deficient counterparts. Equipped with this collection, the authors successfully identified novel kinase regulators in Hedgehog signaling pathway and in activation of Karposi’s Sarcoma herpesvirus. The results are published in May 2nd issue of Cell, titled “Application of active and kinase-deficient kinome collection for identification of kinase regulating Hedgehog signaling”. (Press Release)

Protein Kinase Products

Human Kinome

As the world’s leading gene company, OriGene offers comprehensive product solutions for studying human protein kinases. Our functional kinome cDNA collection was featured in a Cell publication in 2008, “Application of active and kinase-deficient kinome collection for identification of kinase regulating Hedgehog signaling”.

Our products include:

  • 1375 full length human cDNA clones (See list)
  • 345 Kinase-deficient mutants (See list)
  • 886 ORF cDNA clones with epitope tags (See list)
  • HuSH-29 shRNA targeting 512 human genes
  • Pre-designed SYBR primers for qPCR
  • 234 Recombinant proteins
  • primary antibodies

Search all 512 protein kinase genes and related products:
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OriGene offers custom subcloning service for custom tagging, stable selection markers, etc. Contact Technical Support

HuSH-29 shRNA Kinase Collection

HuSH-29 Kinase Collection contains 512 genes cloned in pRFP-C-RS vector allowing researchers to monitor transfection. Learn more…

Catalog No. Description Price Shipping
TR100001 HuSH shRNA kinase collection in RFP vector - constructs individually plated (512 gene targets, 4 shRNA constructs per target, 2 ug/well) Please inquire Immediate
TR100002 HuSH shRNA kinase collection in RFP vector - pooled sets (512 gene targets, 4 shRNA constructs per target pooled, 2 ug/well) Please inquire Immediate

Useful links:

  1. The protein kinase resources
  2. Kinase.com: Genomics, evolution and function of protein kinases
  3. Protein kinase research
  4. Protein Kinase Research Consortium

 

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